Reactive oxygen species (ROS) production in phagocytes is a major defense mechanism
against pathogens. However, the cellular self-protective mechanism against such potential …

The MST/Hippo signalling pathway was first described over a decade ago in Drosophila
melanogaster and the core of the pathway is evolutionary conserved in mammals. The …

Background Alzheimer's disease (AD) is the most prevalent form of age-related dementia,
and its effect on society increases exponentially as the population ages. Accumulating …

Objectives The study aimed to determine whether dental pulp stem cell‐derived exosomes
(DPSC‐Exos) exert protective effects against cerebral ischaemia‐reperfusion (I/R) injury and …

Hippo signaling is an evolutionarily conserved pathway that critically regulates development
and homeostasis of various tissues in response to a wide range of extracellular and …

Apoptotic cell death is a hallmark of the loss of insulin-producing beta cells in all forms of
diabetes mellitus. Current treatments fail to halt the decline in functional beta cell mass, and …

Summary microRNA-132 (miR-132), a known neuronal regulator, is one of the most robustly
downregulated microRNAs (miRNAs) in the brain of Alzheimer's disease (AD) patients …

Microglia are the resident immune cells in the central nervous system and key players
against pathogens and injury. However, persistent microglial activation often exacerbates …

Microglia, the resident immune cells of the central nervous system, responds to brain
disarrangements by becoming activated to contend with brain damage. Here we show that …

Ginkgolide and bilobalide are major trilactone constituent of Ginkgo biloba leaves and have
been shown to exert powerful neuroprotective properties. The aims of this study were to …