Suprabasin—A review

M Pribyl, Z Hodny, I Kubikova - Genes, 2021 - mdpi.com
Among the~ 22,000 human genes, very few remain that have unknown functions. One such
example is suprabasin (SBSN). Originally described as a component of the cornified …

New family members of FG repeat proteins and their unexplored roles during phase separation

Y Shinkai, M Kuramochi, T Miyafusa - Frontiers in Cell and …, 2021 - frontiersin.org
The condensation and compartmentalization of biomacromolecules in the cell are driven by
the process of phase separation. The main effectors of phase separation are intrinsically …

Identification of hub genes associated with obesity-induced hepatocellular carcinoma risk based on integrated bioinformatics analysis

H Ceylan - Medical Oncology, 2021 - Springer
Obesity, which has become one of the biggest public health problems of the twenty-first
century, accompanies many chronic conditions, including cancer. On the other hand, liver …

Newborn infant skin gene expression: Remarkable differences versus adults

MO Visscher, P Hu, AN Carr, CC Bascom, RJ Isfort… - PLoS …, 2021 - journals.plos.org
At birth, human infants are poised to survive in harsh, hostile conditions. An understanding
of the state of newborn skin development and maturation is key to the maintenance of …

Data analysis-oriented stochastic scheduling for cost efficient resource allocation in NFV based MEC network

B Li, F Hou, G Yang, H Zhao… - IEEE Transactions on …, 2023 - ieeexplore.ieee.org
Recently, there has been increasing interest in data analysis services based on MapReduce
framework, which is a programming model and an associated implementation for processing …

Identification and validation of core genes as promising diagnostic signature in hepatocellular carcinoma based on integrated bioinformatics approach

P Kumar, AK Singh, KN Tiwari, SK Mishra… - Scientific Reports, 2022 - nature.com
The primary objective of this investigation was to determine the hub genes of hepatocellular
carcinoma (HCC) through an in silico approach. In the current context of the increased …

Decreased expression of suprabasin induces aberrant differentiation and apoptosis of epidermal keratinocytes: Possible role for atopic dermatitis

M Aoshima, P Phadungsaksawasdi… - Journal of …, 2019 - Elsevier
Background Suprabasin (SBSN), a secreted protein, is expressed in various epithelial
tissues. The role of SBSN in epidermal differentiation and atopic dermatitis (AD) pathology …

Suprabasin-null mice retain skin barrier function and show high contact hypersensitivity to nickel upon oral nickel loading

S Nakazawa, T Shimauchi, A Funakoshi, M Aoshima… - Scientific Reports, 2020 - nature.com
Suprabasin (SBSN) is expressed not only in epidermis but also in epithelial cells of the
upper digestive tract where metals such as nickel are absorbed. We have recently shown …

Suprabasin: Role in human cancers and other diseases

H Tan, L Wang, Z Liu - Molecular Biology Reports, 2022 - Springer
Suprabasin (SBSN), a gene with unknown function located in q13 region of chromosome 19,
was first found to be expressed in the basal layer of the stratified epithelium in mouse and …

A nine-hub-gene signature of metabolic syndrome identified using machine learning algorithms and integrated bioinformatics

G Liu, S Luo, Y Lei, J Wu, Z Huang, K Wang… - …, 2021 - Taylor & Francis
Early risk assessments and interventions for metabolic syndrome (MetS) are limited because
of a lack of effective biomarkers. In the present study, several candidate genes were …