10 Years of belimumab experience: What have we learnt?

RA Levy, T Gonzalez-Rivera, M Khamashta, NL Fox… - Lupus, 2021 - journals.sagepub.com
Systemic lupus erythematosus (SLE) is a chronic autoimmune inflammatory disease
affecting both adults and children. Belimumab is the only biologic approved for SLE, and the …

Treatment of lupus nephritis: consensus, evidence and perspectives

CC Mok, YKO Teng, R Saxena, Y Tanaka - Nature Reviews …, 2023 - nature.com
Despite the continuing development of immunomodulatory agents and supportive care, the
prognosis associated with lupus nephritis (LN) has not improved substantially in the past …

Voclosporin: a novel calcineurin inhibitor for the treatment of lupus nephritis

T van Gelder, E Lerma, K Engelke… - Expert review of clinical …, 2022 - Taylor & Francis
Introduction Lupus nephritis (LN) is a severe manifestation of systemic lupus erythematosus.
Standard-of-care immunosuppressive therapies achieve poor complete renal response …

Complement as a biomarker for systemic lupus erythematosus

M Ayano, T Horiuchi - Biomolecules, 2023 - mdpi.com
Systemic lupus erythematosus (SLE) is a disease of immune complex deposition; therefore,
complement plays a vital role in the pathogenesis of SLE. In general, complement levels in …

Belimumab and antimalarials combined against renal flares in patients treated for extra-renal systemic lupus erythematosus: results from 4 phase III clinical trials

A Gomez, S Jägerback, C Sjöwall, I Parodis - Rheumatology, 2024 - academic.oup.com
Objectives To determine the effect of antimalarial agents (AMA) and different doses and
pharmaceutical forms of belimumab on preventing renal flares in patients with SLE treated …

[HTML][HTML] Белимумаб в лечении системной красной волчанки: 20 лет фундаментальных исследований, 10 лет клинической практики

ЕЛ Насонов, ТВ Попкова, АМ Лила - Научно-практическая …, 2021 - cyberleninka.ru
В настоящее время получены веские доказательства фундаментальной роли
патологической активации В-клеток в патогенезе иммуновоспалительных …

Management of non‐renal manifestations of systemic lupus erythematosus: a systematic literature review for the APLAR consensus statements

N Kasitanon, L Hamijoyo, MT Li, K Oku… - International Journal …, 2022 - Wiley Online Library
The prevalence of systemic lupus erythematosus (SLE) is higher in Asians than Caucasians,
with higher frequency of renal and other major organ manifestations that carry a poorer …

Recommendations for systemic lupus erythematosus: balancing evidence and eminence to facilitate the medical care of a complex disease

G Bertsias - Rheumatic Disease Clinics, 2022 - rheumatic.theclinics.com
Owing to its systemic nature with multiple organs potentially being affected concurrently or
sequentially and at varying degrees of severity, the management of systemic lupus …

Validation of the 2019 EULAR/ACR classification criteria for systemic lupus erythematosus in ANA-positive Chinese patients

YK Chung, LY Ho, C Lee, CH To… - Therapeutic Advances …, 2022 - journals.sagepub.com
Background: The aim of this study was to validate the 2019 European League Against
Rheumatism/American College of Rheumatology (EULAR/ACR) classification criteria for …

Prevention of infective complications in systemic lupus erythematosus: a systematic literature review for the APLAR consensus statements

K Oku, L Hamijoyo, N Kasitanon, MT Li… - International Journal …, 2021 - Wiley Online Library
Systemic lupus erythematosus (SLE) is a more common autoimmune rheumatic disease in
the Asia‐Pacific region. The prognosis of SLE remains unsatisfactory in some Asian …