The species composition of the human gut microbiota is related to overall health, and a
healthy gut microbiome is crucial in maintaining colonization resistance against pathogens …

Clostridioides difficile infection (CDI) is one of the major issues in nosocomial infections.
This bacterium is constantly evolving and poses complex challenges for clinicians, often …

The change of dietary habits in Western societies, including reduced consumption of fiber, is
linked to alterations in gut microbial ecology. Nevertheless, mechanistic connections …

ABSTRACT A disrupted “dysbiotic” gut microbiome engenders susceptibility to the diarrheal
pathogen Clostridioides difficile by impacting the metabolic milieu of the gut. Diet, in …

Clostridioides difficile infection (CDI) imposes a substantial burden on the health care
system in the United States. Understanding the biological basis for the spectrum of C …

ABSTRACT Background & Aim Clostridioides difficile infection (CDI) is the leading cause of
hospital-acquired diarrhea and pseudomembranous colitis. Two protein toxins, TcdA and …

Objective: Inflammatory bowel disease (IBD) is characterized by gut microbiota dysbiosis,
which is also frequently observed in patients with non-alcoholic fatty liver disease. Whether …

Clostridioides difficile causes nosocomial antibiotic-associated diarrhea on a global scale.
Susceptibility to C. difficile infection (CDI) is influenced by the composition and metabolism …

Clostridioides difficile is an urgent antimicrobial-resistant bacterium, causing mild to
moderate and sometimes life-threatening disease. Commensal gut microbes are critical for …

Severe Clostridiodes difficile infection (CDI) is life-threatening and responds poorly to
treatment. Obesity is associated with development of severe CDI. Therefore, to define the …