Multiparametric MRI for characterization of the tumour microenvironment

E Hoffmann, M Masthoff, WG Kunz… - Nature Reviews …, 2024 - nature.com
Our understanding of tumour biology has evolved over the past decades and cancer is now
viewed as a complex ecosystem with interactions between various cellular and non-cellular …

Time-dependent diffusion magnetic resonance imaging: measurement, modeling, and applications

R Ba, L Kang, D Wu - Journal of Zhejiang University-SCIENCE A, 2024 - Springer
Increasingly, attention is being directed towards time-dependent diffusion magnetic
resonance imaging (TDDMRI), a method that reveals time-related changes in the diffusional …

[HTML][HTML] Frequency-dependent diffusion kurtosis imaging in the human brain using an oscillating gradient spin echo sequence and a high-performance head-only …

E Dai, A Zhu, GK Yang, K Quah, ET Tan, E Fiveland… - NeuroImage, 2023 - Elsevier
Measuring the time/frequency dependence of diffusion MRI is a promising approach to
distinguish between the effects of different tissue microenvironments, such as membrane …

[HTML][HTML] Diffusion MRI with free gradient waveforms on a high-performance gradient system: Probing restriction and exchange in the human brain

A Chakwizira, A Zhu, T Foo, CF Westin… - NeuroImage, 2023 - Elsevier
The dependence of the diffusion MRI signal on the diffusion time carries signatures of
restricted diffusion and exchange. Here we seek to highlight these signatures in the human …

In vivo mapping of cellular resolution neuropathology in brain ischemia with diffusion MRI

D Wu, HH Lee, R Ba, V Turnbill, X Wang, Y Luo… - Science …, 2024 - science.org
Noninvasive mapping of cellular pathology can provide critical diagnostic and prognostic
information. Recent advances in diffusion magnetic resonance imaging enabled in vivo …

Diffusion-time dependent diffusion MRI: effect of diffusion-time on microstructural mapping and prediction of prognostic features in breast cancer

R Ba, X Wang, Z Zhang, Q Li, Y Sun, J Zhang… - European Radiology, 2023 - Springer
Objectives This study aimed to evaluate the effect of achievable td on the accuracy of
microstructural mapping based on simulation and patient experiments, and investigate the …

tDKI-Net: A Joint qT Space Learning Network for Diffusion-Time-Dependent Kurtosis Imaging

T Zheng, R Ba, Y Huang, D Wu - IEEE Journal of Biomedical …, 2024 - ieeexplore.ieee.org
Time-dependent diffusion magnetic resonance imaging (TDDMRI) is useful for the non-
invasive characterization of tissue microstructure. These models require both densely …

Diffusional kurtosis time dependence and the water exchange rate for the multi‐compartment Kärger model

JH Jensen - Magnetic Resonance in Medicine, 2024 - Wiley Online Library
Purpose To demonstrate an analytic formula giving the time dependence of the diffusional
kurtosis for the Kärger model (KM) with an arbitrary number of exchanging compartments …

hydrogel‐based mimics of prostate cancer with matched relaxation, diffusion and kurtosis for validating multi‐parametric MRI

D Malyarenko, S Ono, TJE Lynch… - Medical …, 2024 - Wiley Online Library
Background Protocol standardization and optimization for clinical translation of emerging
quantitative multiparametric (mp) MRI biomarkers of high‐risk prostate cancer requires …

AUA-dE: An Adaptive Uncertainty Guided Attention for Diffusion MRI Models Estimation

T Zheng, R Ba, X Wang, C Ye, D Wu - International Conference on Medical …, 2023 - Springer
Diffusion MRI (dMRI) is a well-established tool for probing tissue microstructure properties.
However, advanced dMRI models commonly have multiple compartments that are highly …