Abstract Glucagon-like peptide-1 (GLP-1), an incretin hormone, is released from intestinal L-
cells in response to nutrients. GLP-1 lowers blood glucose levels by stimulating insulin …

Endogenous pancreatic β cell regeneration is a potential strategy for β cell expansion or
neogenesis to treat diabetes. Regeneration can occur through stimulation of existing β cell …

Diabetes mellitus is a major public health problem worldwide. Oxidative stress plays a
pivotal role in the pathogenesis of diabetes as it is one of the inevitable outcomes of the …

Diabetes mellitus is a common metabolic/endocrine disorder characterized by inadequate
control of carbohydrate metabolism and causes serious health issues. This study evaluates …

Objective To evaluate the effect of hydroethanolic extract of yacon on the hyperglycemia
induced by streptozotocin (STZ) in neonatal rats. Methods Wistar rats aged two days old …

Offspring of diabetic mothers are susceptible to developing type 2 diabetes due to
pancreatic islet dysfunction. However, the initiating molecular pathways leading to offspring …

Background We aim to investigate the effects of dipeptidyl-peptidase-4 inhibitor (Vildagliptin-
VG) on DDR-1 as a marker for endocrine progenitor cells, β-cell regeneration, and apoptosis …

The aim of the present study was to evaluate the antidiabetic activity of the aqueous extract
of Citrullus colocynthis L Schrad.(colocynth) fruits, CCFaq and Bryonia dioica Jacq.(White …

Background: Diabetes mellitus is a metabolic disorder causing dysfunctional regulation of
carbohydrate metabolism and contributing to multiple serious health challenges worldwide …

Aim: The INK4b-ARF-INK4a locus in the chromosome 9p21 region is known to play an
important role in the development of atherosclerosis. The INK4/ARF transcript p16 INK4a …