[HTML][HTML] Resveratrol: A Multifaceted Guardian against Anxiety and Stress Disorders—An Overview of Experimental Evidence

VE Tseilikman, OB Tseilikman, ON Yegorov… - Nutrients, 2024 - mdpi.com
The medicinal properties of resveratrol have garnered increasing attention from researchers.
Extensive data have been accumulated on its use in treating cardiovascular diseases …

Natural polyphenols as therapeutic candidates for mitigating neuropsychiatric symptoms in post-traumatic stress disorder: Evidence from preclinical studies

P Raise-Abdullahi, M Rezvani, F Yousefi… - Progress in Neuro …, 2024 - Elsevier
Post-traumatic stress disorder (PTSD) is a challenging mental health condition that affects
millions of people worldwide after they experience traumatic events. The current …

[HTML][HTML] Unraveling the Liver–Brain Axis: Resveratrol's Modulation of Key Enzymes in Stress-Related Anxiety

VE Tseilikman, OB Tseilikman, VA Shevyrin… - Biomedicines, 2024 - mdpi.com
Stress-related anxiety disorders and anxiety-like behavior in post-traumatic stress disorder
(PTSD) are associated with altered neurocircuitry pathways, neurotransmitter systems, and …

Resveratrol analogues and metabolites selectively inhibit human and rat 11β-hydroxysteroid dehydrogenase 1 as the therapeutic drugs: structure–activity relationship …

C Hu, Y Zhai, H Lin, H Lu, J Zheng, C Wen… - SAR and QSAR in …, 2024 - Taylor & Francis
Resveratrol is converted to various metabolites by gut microbiota. Human and rat liver 11β-
hydroxysteroid dehydrogenase 1 (11β-HSD1) are critical for glucocorticoid activation, while …

Design, one-pot synthesis, computational and biological evaluation of diaryl benzimidazole derivatives as MEK inhibitors

T Ram, AK Singh, P Pathak, A Kumar… - Journal of …, 2024 - Taylor & Francis
MEK mutations are more common in various human malignancies, such as pancreatic
cancer (70–90%), mock melanoma (50%), liver cancer (20–40%), colorectal cancer (25 …

[PDF][PDF] РОЛЬ КОМБИНИРОВАННОЙ АНТИГЛЮКОКОРТИКОИДНОЙ, АНТИОКСИДАНТНОЙ И ПРОТИВОВОСПАЛИТЕЛЬНОЙ ТЕРАПИИ В ЛЕЧЕНИИ …

ЮВ Быков, РА Беккер - academia.edu
Представлено описание двух клинических случаев фармакорезистентного
посттравматического стрессового расстройства. В каждом из них достичь полной или …

Unveiling the Link: Exploring Mitochondrial Dysfunction as a Probable Mechanism of Hepatic Damage in Post-Traumatic Stress Syndrome

MV Kondashevskaya, LM Mikhaleva… - International Journal of …, 2023 - mdpi.com
PTSD is associated with disturbed hepatic morphology and metabolism. Neuronal
mitochondrial dysfunction is considered a subcellular determinant of PTSD, but a link …