Carbapenem antibiotics are the most effective antimicrobials for the treatment of infections
caused by the most resistant bacteria. They belong to the category of β-lactams that include …

Adequately controlling the source of infection and prescribing appropriately antibiotic
therapy are the cornerstones of the management of patients with intra-abdominal infections …

Biofilms related to human infection have high levels of pathogenicity due to their resistance
to antimicrobial agents. The discovery of antibiofilm agents is necessary. One approach to …

Bacterial vaginosis (BV) is the most common vaginal infection affecting women worldwide.
This infection is characterized by the loss of the dominant Lactobacillus community in the …

Antimicrobial resistance (AMR) poses a significant global health challenge, necessitating
advanced predictive models to support clinical decision-making. In this study, we explore …

In recent years, bacterial pathogens have developed resistance to antimicrobial agents that
have created a global threat to human health and environment. As a novel approach to …

Therapeutic drug monitoring (TDM) of antibiotics (ATB) in patients with serious bacterial
infections allows optimization of the efficacy of the treatment while reducing the risk of …

Although the spread of plasmid-mediated antibiotic-resistant bacteria is a public health
concern, food contamination with plasmid-mediated antibiotic-resistant Escherichia coli in …

New and creative approaches are required to treat chronic infections caused by increasingly
drug-resistant strains of bacteria. One strategy is the use of cellular therapy employing …

ABSTRACT A wide variety of clinically observed single amino acid substitutions in the Ω-
loop region have been associated with increased minimum inhibitory concentrations and …