Case series are a commonly reported study design, but the label “case series” is used
inconsistently and sometimes incorrectly. Mislabeling impairs the appropriate indexing and …

The selective serotonin reuptake inhibitors (SSRIs) are considered the first-line
pharmacological treatment for PTSD. However, even when treated with this class of drugs …

Background The clinical case report has a long-standing tradition in the medical literature.
While its scientific significance has become smaller as more advanced research methods …

Introduction Case series have been a long held tradition within the surgical literature and
are still frequently published. Reporting guidelines can improve transparency and reporting …

Background Combining biologics and small molecules could potentially overcome the
plateau of drug efficacy in inflammatory bowel disease (IBD). We conducted a systematic …

A core set of clinical research designs have stood the test of time and are repeatedly used in
most studies. No single research design is best to answer all research questions, and every …

Complementary and alternative medicine use is common amongst cancer patients. In many
surveys, herbal medicines are amongst the most commonly used group of treatments …

Background & Aims Fecal microbiota–based therapies include conventional fecal microbiota
transplant and US Food and Drug Administration–approved therapies, fecal microbiota live …

INTRODUCTION: Popliteal entrapment syndrome (PES) is a rare but important cause of
intermittent claudication in young people. Controversy exists about optimal strategies for …

Background Children with chronic illnesses are at increased risk for reductions in bone
strength and subsequent fractures (osteoporosis), either due to the impact of the underlying …