Primary microcephaly (MCPH, for “microcephaly primary hereditary”) is a disorder of brain
development that results in a head circumference more than 3 standard deviations below …

The organization of microtubule networks is crucial for controlling chromosome segregation
during cell division, for positioning and transport of different organelles, and for cell polarity …

Autosomal recessive primary microcephaly (MCPH;“small head syndrome”) is a rare,
heterogeneous disease arising from the decreased production of neurons during brain …

Abstract γ-Tubulin ring complex (γ-TuRC) is the major microtubule-nucleating factor. After
nucleation, microtubules can be released from γ-TuRC and stabilized by other proteins …

The cerebrovascular disorder moyamoya disease (MMD) was first described in 1957 in
Japan, and is typically considered to be an Asian-specific disease. However, it is globally …

Autosomal recessive primary microcephaly (MCPH; MicroCephaly Primary Hereditary) is a
genetically heterogeneous neurodevelopmental disorder characterized by a significantly …

Progeroid disorders make up a heterogeneous group of very rare hereditary diseases
characterized by clinical signs that often mimic physiological aging in a premature manner …

Congenital microcephaly (CM) exhibits broad clinical and genetic heterogeneity and is thus
categorized into several subtypes. However, the recent bloom of disease–gene discoveries …

The centrosome is a membrane-less organelle consisting of a pair of barrel-shaped
centrioles and pericentriolar material and functions as the major microtubule-organizing …

Red blood cells are produced by terminal erythroid differentiation, which involves the
dramatic morphological transformation of erythroblasts into enucleated reticulocytes …