Gastric bypass compared with sleeve gastrectomy for nonalcoholic fatty liver disease: a systematic review and meta-analysis

MB de Brito e Silva, F Tustumi, AA de Miranda Neto… - Obesity Surgery, 2021 - Springer
The effects of bariatric procedures on nonalcoholic fatty liver disease (NAFLD) and
nonalcoholic steatohepatitis (NASH) remain unclear. A systematic review and meta-analysis …

Changes in bile acid metabolism, transport, and signaling as central drivers for metabolic improvements after bariatric surgery

MG Browning, BM Pessoa, J Khoraki… - Current obesity reports, 2019 - Springer
Abstract Purpose of Review We review current evidence regarding changes in bile acid (BA)
metabolism, transport, and signaling after bariatric surgery and how these might bolster fat …

Metabolic shift precedes the resolution of inflammation in a cohort of patients undergoing bariatric and metabolic surgery

JR Villarreal-Calderon, R Cuellar-Tamez… - Scientific Reports, 2021 - nature.com
Bariatric and metabolic surgery has shown to promote weight loss and reduce systemic
inflammation. However, the sequence and timing of events regarding metabolic …

Hepatic Zbtb18 (Zinc Finger and BTB Domain Containing 18) alleviates hepatic steatohepatitis via FXR (Farnesoid X Receptor)

L Zhang, J Chen, X Yang, C Shen, J Huang… - … and Targeted Therapy, 2024 - nature.com
A lasting imbalance between fatty acid synthesis and consumption leads to non-alcoholic
fatty liver disease (NAFLD), coupled with hepatitis and insulin resistance. Yet the details of …

[HTML][HTML] Emodin palliates high-fat diet-induced nonalcoholic fatty liver disease in mice via activating the farnesoid X receptor pathway

C Shen, Z Pan, S Wu, M Zheng, C Zhong, X Xin… - Journal of …, 2021 - Elsevier
Abstract Background Cassia mimosoides Linn (CMD) is a traditional Chinese herb that
clears liver heat and dampness. It has been widely administered in clinical practice to treat …

Gut microbiome and metabolites in patients with NAFLD and after bariatric surgery: a comprehensive review

J Hoozemans, M de Brauw, M Nieuwdorp, V Gerdes - Metabolites, 2021 - mdpi.com
The prevalence of non-alcoholic fatty liver disease (NAFLD) is increasing, as are other
manifestations of metabolic syndrome such as obesity and type 2 diabetes. NAFLD is …

Bariatric surgery for diabetic comorbidities: A focus on hepatic, cardiac and renal fibrosis

H Ding, Y Zhang, X Ma, Z Zhang, Q Xu, C Liu… - Frontiers in …, 2022 - frontiersin.org
Continuously rising trends in diabetes render this disease spectrum an epidemic proportion
worldwide. As the disease progresses, the pathological effects of diabetes may impair the …

ASMBS position statement on the impact of metabolic and bariatric surgery on nonalcoholic steatohepatitis

GS Mazzini, T Augustin, S Noria… - Surgery for Obesity and …, 2022 - soard.org
ASMBS Position Statement on the Impact of Metabolic and Bariatric Surgery on
Nonalcoholic Steatohepatitis - Surgery for Obesity and Related Diseases Skip to Main …

Gastric bypass increases circulating bile acids and activates hepatic farnesoid X receptor (FXR) but requires intact peroxisome proliferator activator receptor alpha …

GS Mazzini, J Khoraki, MG Browning, J Wu… - Journal of …, 2021 - Elsevier
Background We interrogate effects of gastric bypass (RYGB), compared with a low-calorie
diet, on bile acid (BA), liver fat, and FXR, PPARα, and targets in rats with obesity and non …

Tumor suppressive maspin-sensitized prostate cancer to drug treatment through negative regulating androgen receptor expression

S Tang, X Lian, J Jiang, H Cheng, J Guo… - Frontiers in Cell and …, 2020 - frontiersin.org
Overactivation of androgen receptor (AR)-mediated signal has been extensively implicated
in prostate cancer (CaP) development, progression, and recurrence, which makes it an …