Background: Otoconia are bio‐crystals that couple mechanic forces to the sensory hair cells
in the utricle and saccule, a process essential for us to sense linear acceleration and gravity …

The vertebrate inner ear is a sensory organ of exquisite design and sensitivity. It responds to
sound, gravity and movement, serving both auditory (hearing) and vestibular (balance) …

All epithelial components of the inner ear, including sensory hair cells and innervating
afferent neurons, arise by patterning and differentiation of epithelial progenitors residing in a …

SOX2 is essential for maintaining neurosensory stem cell properties, although its
involvement in the early neurosensory development of cranial placodes remains unclear. To …

Single-cell atlases pose daunting computational challenges pertaining to the integration of
spatial and temporal information and the visualization of trajectories across large atlases …

Vertebrate cranial placodes are crucial contributors to the vertebrate cranial sensory
apparatus. Their evolutionary origin has attracted much attention from evolutionary and …

Melanocyte development is orchestrated by a complex interconnecting regulatory network of
genes and synergistic interactions. Piebaldism and Waardenburg syndrome are …

Gonadotropin releasing hormone (GnRH) neurons are hypothalamic neuroendocrine cells
that control sexual reproduction. During embryonic development, GnRH neurons migrate …

We review the development and evolution of the ear neurosensory cells, the aggregation of
neurosensory cells into an otic placode, the evolution of novel neurosensory structures …

The vertebrate inner ear is a precision sensory organ, acting as both a microphone to
receive sound and an accelerometer to detect gravity and motion. It consists of a series of …