Continuing Medical Education examination CONTINUING MEDICAL EDUCATION
ARTICLECredit can now be obtained, free for a limited time, by reading the following review …

Allergic and autoimmune diseases are forms of immune hypersensitivity that increasingly
cause chronic ill health. Most current therapies treat symptoms rather than addressing …

We report that programmed death ligand 2 (PD-L2), a known ligand of PD-1, also binds to
repulsive guidance molecule b (RGMb), which was originally identified in the nervous …

Antigen-specific immunotherapy combats autoimmunity or allergy by reinstating
immunological tolerance to target antigens without compromising immune function …

Intradermal administration of short overlapping peptides derived from chain 1 of the cat
allergen Fel d 1 (FC1P) that did not cross-link IgE, elicited isolated late asthmatic reactions …

Publisher Summary This chapter discusses the mechanisms and therapeutic applications of
oral tolerance. The most striking characteristic of the gut mucosa is the abundance of the …

Peptide immunotherapy using multiple predominant allergen-specific T cell epitopes is a
safe and promising strategy for the control of type I allergy. In this study, we developed …

Th2 cells play a critical role in the pathogenesis of allergy and asthma. However, the
immunological mechanisms that downmodulate and protect against the development of …

The role of TH2 cells in the pathogenesis of allergy and asthma has been well described.
However, the immunologic mechanisms that downmodulate and protect against the …

There is now overwhelming evidence to support a major role for T cells in asthma, in
particular the involvement of T helper type 2 (Th2) cells in atopic allergic asthma as well as …