Histone deacetylases: Molecular mechanisms and therapeutic implications for muscular dystrophies

M Sandonà, G Cavioli, A Renzini, A Cedola… - International Journal of …, 2023 - mdpi.com
Histone deacetylases (HDACs) are enzymes that regulate the deacetylation of numerous
histone and non-histone proteins, thereby affecting a wide range of cellular processes …

Natural products: Potential therapeutic agents to prevent skeletal muscle atrophy

A Yadav, SS Yadav, S Singh, R Dabur - European Journal of …, 2022 - Elsevier
The skeletal muscle (SkM) is the largest organ, which plays a vital role in controlling
musculature, locomotion, body heat regulation, physical strength, and metabolism of the …

Polyphenols and their potential role in preventing skeletal muscle atrophy

S Salucci, E Falcieri - Nutrition Research, 2020 - Elsevier
Skeletal muscle atrophy is the consequence of various conditions, such as disuse,
denervation, fasting, aging, and disease. Even if the underlying molecular mechanisms are …

Oral administration of plumbagin is beneficial in in vivo models of Duchenne muscular dystrophy through control of redox signaling

D Cervia, S Zecchini, L Pincigher, P Roux-Biejat… - Free Radical Biology …, 2024 - Elsevier
Duchenne muscular dystrophy (DMD) is a progressive muscle-wasting disease. Recently
approved molecular/gene treatments do not solve the downstream inflammation-linked …

Natural bioactive flavonoids as promising agents in alleviating exercise-induced fatigue

Y Liu, X Shen, M Sha, Z Feng, Y Liu - Food Bioscience, 2023 - Elsevier
Exercise-induced fatigue is a common phenomenon caused by prolonged strenuous
exercise and physical labor as a feeling of exhaustion and reduction of muscle performance …

Flavonoids: Nutraceutical potential for counteracting muscle atrophy

C Kim, JK Hwang - Food science and biotechnology, 2020 - Springer
Skeletal muscle plays a vital role in the conversion of chemical energy into physical force.
Muscle atrophy, characterized by a reduction in muscle mass, is a symptom of chronic …

[HTML][HTML] The contribution of biological sex to heat stress-mediated outcomes in growing pigs

TE Rudolph, M Roths, AD Freestone, RP Rhoads… - animal, 2024 - Elsevier
Heat stress (HS) negatively impacts a variety of production parameters in growing pigs;
however, the impact of biological sex on the HS response is largely unknown. To address …

[PDF][PDF] Is exercise the right medicine for dystrophic muscle

HR Spaulding, JT Selsby - Med Sci Sports Exerc, 2018 - paulogentil.com
Introduction: Duchenne muscular dystrophy (DMD) is a neuromuscular disease caused by a
dystrophin protein deficiency. Dystrophin functions to stabilize and protect the muscle fiber …

Molecular pathways involved in the control of contractile and metabolic properties of skeletal muscle fibers as potential therapeutic targets for Duchenne muscular …

A Bonato, G Raparelli, M Caruso - Frontiers in Physiology, 2024 - frontiersin.org
Duchenne muscular dystrophy (DMD) is caused by mutations in the gene encoding
dystrophin, a subsarcolemmal protein whose absence results in increased susceptibility of …

The regulatory role of dietary factors in skeletal muscle development, regeneration and function

L Wang, Z Xu, D Ling, J Li, Y Wang… - Critical Reviews in Food …, 2022 - Taylor & Francis
Skeletal muscle plays a crucial role in motor function, respiration, and whole-body energy
homeostasis. How to regulate the development and function of skeletal muscle has become …