Twenty-five years of clinical applications using adaptive optics ophthalmoscopy

JIW Morgan, TYP Chui, K Grieve - Biomedical Optics Express, 2022 - opg.optica.org
Twenty-five years ago, adaptive optics (AO) was combined with fundus photography,
thereby initiating a new era in the field of ophthalmic imaging. Since that time, clinical …

Phenotyping and genotyping inherited retinal diseases: Molecular genetics, clinical and imaging features, and therapeutics of macular dystrophies, cone and cone-rod …

M Georgiou, AG Robson, K Fujinami… - Progress in retinal and …, 2024 - Elsevier
Inherited retinal diseases (IRD) are a leading cause of blindness in the working age
population and children. The scope of this review is to familiarise clinicians and scientists …

[HTML][HTML] Inherited retinal degenerations: current landscape and knowledge gaps

JL Duncan, EA Pierce, AM Laster… - … vision science & …, 2018 - tvst.arvojournals.org
Inherited retinal degenerations (IRDs) represent a diverse group of progressive, visually
debilitating diseases that can lead to blindness in which mutations in genes that are critical …

[HTML][HTML] Restoration of visual function in advanced disease after transplantation of purified human pluripotent stem cell-derived cone photoreceptors

J Ribeiro, CA Procyk, EL West, M O'Hara-Wright… - Cell reports, 2021 - cell.com
Age-related macular degeneration and other macular diseases result in the loss of light-
sensing cone photoreceptors, causing irreversible sight impairment. Photoreceptor …

[HTML][HTML] Vision science and adaptive optics, the state of the field

S Marcos, JS Werner, SA Burns, WH Merigan, P Artal… - Vision research, 2017 - Elsevier
Adaptive optics is a relatively new field, yet it is spreading rapidly and allows new questions
to be asked about how the visual system is organized. The editors of this feature issue have …

Adaptive optics: principles and applications in ophthalmology

E Akyol, AM Hagag, S Sivaprasad, AJ Lotery - Eye, 2021 - nature.com
This is a comprehensive review of the principles and applications of adaptive optics (AO) in
ophthalmology. It has been combined with flood illumination ophthalmoscopy, scanning …

[HTML][HTML] Achromatopsia: genetics and gene therapy

S Michalakis, M Gerhardt, G Rudolph… - Molecular diagnosis & …, 2022 - Springer
Achromatopsia (ACHM), also known as rod monochromatism or total color blindness, is an
autosomal recessively inherited retinal disorder that affects the cones of the retina, the type …

The cone dysfunction syndromes

J Aboshiha, AM Dubis, J Carroll… - British Journal of …, 2016 - bjo.bmj.com
The cone dysfunction syndromes are a heterogeneous group of inherited, predominantly
stationary retinal disorders characterised by reduced central vision and varying degrees of …

Achromatopsia: clinical features, molecular genetics, animal models and therapeutic options

N Hirji, J Aboshiha, M Georgiou, J Bainbridge… - Ophthalmic …, 2018 - Taylor & Francis
Achromatopsia is an autosomal recessive condition, characterised by reduced visual acuity,
impaired colour vision, photophobia and nystagmus. The symptoms can be profoundly …

[HTML][HTML] Gene augmentation therapy restores retinal function and visual behavior in a sheep model of CNGA3 achromatopsia

E Banin, E Gootwine, A Obolensky, R Ezra-Elia… - Molecular therapy, 2015 - cell.com
Achromatopsia is a hereditary form of day blindness caused by cone photoreceptor
dysfunction. Affected patients suffer from congenital color blindness, photosensitivity, and …