In this review the current state‐of‐the‐art of S‐adenosylmethionine (SAM)‐dependent
methyltransferases and SAM are evaluated. Their structural classification and diversity is …

Breast cancer is a leading cause of death among women worldwide. Dysbiosis, an aberrant
composition of the microbiome, characterizes breast cancer. In this review we discuss the …

Flavonoids and isoflavonoids are polyphenolic secondary metabolites usually produced by
plants adapting to changing ecological environments over a long period of time. Therefore …

Ovarian cancer is characterized by dysbiosis, referred to as oncobiosis in neoplastic
diseases. In ovarian cancer, oncobiosis was identified in numerous compartments, including …

O-Methylation catalyzed by O-methyltransferases (OMTs) is an important modification of
flavonoids for improving the transport efficiency across membranes and metabolic stability in …

Abstract About 20,100 research publications dated 2000–2017 were recovered searching
the PubMed and Web of Science databases for Streptomyces, which are the richest known …

The microbiome is capable of modulating the bioavailability of chemotherapy drugs, mainly
due to metabolizing these agents. Multiple cytostatic bacterial metabolites were recently …

Volatiles are important for plant root stress resistance. The diseases in tea root are serious,
causing major losses. The volatile composition in tea root and whether it can resist diseases …

Streptomyces peucetius ATCC 27952 is a filamentous soil bacterium with potential to
produce anthracyclines such as doxorubicin (DXR) and daunorubicin (DNR), which are …

Secondary metabolites are assembled by enzymes that often perform reactions with high
selectivity and specificity. Many of these enzymes also tolerate variations in substrate …