[HTML][HTML] Associations between white matter hyperintensity burden, cerebral blood flow and transit time in small vessel disease: an updated meta-analysis

CR Stewart, MS Stringer, Y Shi, MJ Thrippleton… - Frontiers in …, 2021 - frontiersin.org
Cerebral small vessel disease (SVD) is a major contributor to stroke and dementia,
characterized by white matter hyperintensities (WMH) on neuroimaging. WMH are …

[HTML][HTML] Sex differences in cerebral small vessel disease: a systematic review and meta-analysis

L Jiménez-Sánchez, OKL Hamilton, U Clancy… - Frontiers in …, 2021 - frontiersin.org
Background: Cerebral small vessel disease (SVD) is a common cause of stroke, mild
cognitive impairment, dementia and physical impairments. Differences in SVD incidence or …

Current state and guidance on arterial spin labeling perfusion MRI in clinical neuroimaging

T Lindner, DS Bolar, E Achten, F Barkhof… - Magnetic resonance …, 2023 - Wiley Online Library
This article focuses on clinical applications of arterial spin labeling (ASL) and is part of a
wider effort from the International Society for Magnetic Resonance in Medicine (ISMRM) …

Association of intensive vs standard blood pressure control with cerebral blood flow: secondary analysis of the SPRINT MIND randomized clinical trial

S Dolui, JA Detre, SA Gaussoin, JS Herrick… - JAMA …, 2022 - jamanetwork.com
Importance Antihypertensive treatments benefit cerebrovascular health and cognitive
function in patients with hypertension, but it is uncertain whether an intensive blood pressure …

Oxygen metabolic stress and white matter injury in patients with cerebral small vessel disease

P Kang, C Ying, Y Chen, AL Ford, H An, JM Lee - Stroke, 2022 - Am Heart Assoc
Background: Chronic hypoxia-ischemia is a putative mechanism underlying the
development of white matter hyperintensities (WMH) and microstructural disruption in …

[HTML][HTML] Imaging the neurovascular unit in health and neurodegeneration: a scoping review of interdependencies between MRI measures

E Rowsthorn, W Pham, MR Nazem-Zadeh… - Fluids and Barriers of …, 2023 - Springer
The neurovascular unit (NVU) is a complex structure that facilitates nutrient delivery and
metabolic waste clearance, forms the blood–brain barrier (BBB), and supports fluid …

[HTML][HTML] New insights in addressing cerebral small vessel disease: association with the deep medullary veins

Z Xu, F Li, B Wang, D Xing, Y Pei, B Yang… - Frontiers in Aging …, 2020 - frontiersin.org
Objective To assess the suitability of deep medullary vein visibility in susceptibility weighted
imaging—magnetic resonance imaging studies as a method for the diagnosis and …

[HTML][HTML] Regional contribution of vascular dysfunction in white matter dementia: clinical and neuropathological insights

J Pansieri, G Hadley, A Lockhart, M Pisa… - Frontiers in …, 2023 - frontiersin.org
The maintenance of adequate blood supply and vascular integrity is fundamental to ensure
cerebral function. A wide range of studies report vascular dysfunction in white matter …

Increased white matter glycolysis in humans with cerebral small vessel disease

MR Brier, T Blazey, ME Raichle, JC Morris… - Nature aging, 2022 - nature.com
White matter lesions in cerebral small vessel disease are related to ischemic injury and
increase the risk of stroke and cognitive decline. Pathological changes due to cerebral small …

[HTML][HTML] Abnormal cerebral blood flow and functional connectivity strength in subjects with white matter hyperintensities

H Huang, K Zhao, W Zhu, H Li, W Zhu - Frontiers in neurology, 2021 - frontiersin.org
White matter hyperintensities (WMHs) are common neuroimaging findings in the aging
population and are associated with various clinical symptoms, especially cognitive …