Creutzfeldt–Jakob disease (CJD) is a rapidly progressive, fatal and transmissible
neurodegenerative disease associated with the accumulation of misfolded prion protein in …

Chronic wasting disease (CWD) is a prion disease found in both free-ranging and farmed
cervids. Susceptibility of these animals to CWD is governed by various exogenous and …

Chronic wasting disease (CWD) has been identified in 30 states in the United States, four
provinces in Canada, and recently emerged in Scandinavia. The association of CWD prions …

Chronic wasting disease (CWD) is a prion disease affecting deer, elk and moose in North
America and reindeer, moose and red deer in Northern Europe. Pathogenesis is driven by …

Prions are novel pathogens that are composed entirely of PrP Sc, the self-templating
conformation of the host prion protein, PrP C. Prion strains are operationally defined as a …

Chronic wasting disease (CWD) is an infectious and fatal prion disease occurring in the
family Cervidae. To update the research community regarding the status quo of CWD …

Chronic wasting disease (CWD) is a transmissible prion disease of the cervidae family.
ELISA and IHC tests performed postmortem on the medial retropharyngeal lymph nodes …

Prion diseases are caused by the conversion of physiological PrPC into the pathogenic
misfolded protein PrPSc, conferring new properties to PrPSc that vary upon prion strains. In …

Prions or prion-like aggregates such as those composed of PrP, α-synuclein, and tau are
key features of proteinopathies such as prion, Parkinson's and Alzheimer's diseases …

Infectivity associated with prion disease has been demonstrated in blood throughout the
course of disease, yet the ability to detect blood-borne prions by in vitro methods remains …