Effect of glucagon‐like peptide‐1 receptor agonists on body weight in adults with obesity without diabetes mellitus—a systematic review and meta‐analysis of …

J Iqbal, HX Wu, N Hu, YH Zhou, L Li, F Xiao… - Obesity …, 2022 - Wiley Online Library
Clinical trials have investigated the weight loss effect of glucagon‐like peptide‐1 receptor
agonists (GLP‐1 RA) in adults with obesity without diabetes mellitus, but results for weight …

Weight loss variability with SGLT2 inhibitors and GLP‐1 receptor agonists in type 2 diabetes mellitus and obesity: mechanistic possibilities

E Brown, JPH Wilding, TM Barber, U Alam… - Obesity …, 2019 - Wiley Online Library
We are facing a global epidemic of obesity and type 2 diabetes. Weight loss, in the context of
obesity and type 2 diabetes, may improve glycaemic control and weight‐related …

Effects of the once-daily GLP-1 analog liraglutide on gastric emptying, glycemic parameters, appetite and energy metabolism in obese, non-diabetic adults

J Van Can, B Sloth, CB Jensen, A Flint… - International journal of …, 2014 - nature.com
Objective: We investigated the effects of liraglutide on gastric emptying, glycemic
parameters, appetite and energy metabolism in obese non-diabetic individuals. Design …

Obesity: Current and potential pharmacotherapeutics and targets

V Narayanaswami, LP Dwoskin - Pharmacology & therapeutics, 2017 - Elsevier
Obesity is a global epidemic that contributes to a number of health complications including
cardiovascular disease, type 2 diabetes, cancer and neuropsychiatric disorders …

Glucagon-like peptide-1 receptor agonists and dual glucose-dependent insulinotropic polypeptide/glucagon-like peptide-1 receptor agonists in the treatment of …

EM Muzurović, Š Volčanšek… - Journal of …, 2022 - journals.sagepub.com
The obesity pandemic is accompanied by increased risk of developing metabolic syndrome
(MetS) and related conditions: non-alcoholic fatty liver disease (NAFLD)/non-alcoholic …

Weight loss effect of glucagon‐like peptide‐1 mimetics on obese/overweight adults without diabetes: A systematic review and meta‐analysis of randomized controlled …

F Zhang, Y Tong, N Su, Y Li, L Tang… - Journal of …, 2015 - Wiley Online Library
摘要背景: 胰高血糖素样肽‐1 (glucagon‐like peptide 1, GLP‐1) 受体激动剂对维持糖尿病患者
的体重有益. 我们通过分析以往的随机对照试验来了解该类药物在非糖尿病的肥胖/超重人群中 …

Weight management in type 2 diabetes: current and emerging approaches to treatment

L Van Gaal, A Scheen - Diabetes care, 2015 - Am Diabetes Assoc
Diabetes is a growing global health concern, as is obesity. Diabetes and obesity are
intrinsically linked: obesity increases the risk of diabetes and also contributes to disease …

[HTML][HTML] The weight-loss effect of GLP-1RAs glucagon-like peptide-1 receptor agonists in non-diabetic individuals with overweight or obesity: a systematic review with …

Y Liu, B Ruan, H Jiang, S Le, Y Liu, X Ao… - The American Journal of …, 2023 - Elsevier
Background Glucagon-like peptide-1 receptor agonists (GLP-1RAs) are new drugs for the
treatment of obesity. Objective To assess the weight-loss effects of GLP-1RAs in the …

The effect of glucagon-like peptide-1 receptor agonist therapy on body mass index in adolescents with severe obesity: a randomized, placebo-controlled, clinical trial

AS Kelly, KD Rudser, BM Nathan, CK Fox… - JAMA …, 2013 - jamanetwork.com
Importance Medical treatment options for pediatric obesity remain limited. Glucagon-like
peptide-1 (GLP-1) receptor agonists induce weight loss by suppressing appetite and …

The role of glucagon‐like peptide‐1 impairment in obesity and potential therapeutic implications

S Madsbad - Diabetes, Obesity and Metabolism, 2014 - Wiley Online Library
The hormone glucagon‐like peptide‐1 (GLP‐1) is released from the gut in response to food
intake. It acts as a satiety signal, leading to reduced food intake, and also as a regulator of …