Diabetes mellitus (DM) has become a vital societal problem as epidemiological studies
demonstrate the increasing incidence of type 1 and type 2 diabetes. Lesions observed in the …

Pericytes (PCs) are specialized cells located abluminal of endothelial cells (ECs) on
capillaries, embedded within the same basement membrane. They are essential regulators …

Ferulic acid (FA) is an antioxidant compound that can prevent ROS-related diseases, but
due to its poor solubility, therapeutic efficacy is limited. One strategy to improve the …

Background Crosstalk between pericytes and endothelial cells is critical for ocular
neovascularization. Endothelial cells secrete platelet-derived growth factor (PDGF)-BB and …

Purpose: Growth factors and inflammatory and angiogenetic proteins are involved in the
development of retinopathy of prematurity (ROP). However, no early biochemical markers …

The aim of the present study was to investigate the role of microRNA (miR)‑133b in high‑
glucose‑induced human retinal endothelial cells (hRECs), particularly regarding its potential …

High intraocular pressure causes retinal ganglion cell injury in primary and secondary
glaucoma diseases, yet the molecular landscape characteristics of retinal cells under high …

Diabetic retinopathy (DR) is a leading cause of blindness worldwide. It is typically diagnosed
through visible vascular changes but is preceded by subtle, early alterations that current …

Diabetes is closely related to hearing loss, but its specific pathogenesis is not clear.
Cochlear stria vascularis and pericytes play an important role in hearing. The purpose of this …

La Organización Mundial de la Salud (OMS) definió el término ictus en 1978 como un
síndrome clínico de origen vasculogénico caracterizado por signos de cambios locales o …