A systematic review of the protective effects of silymarin/silibinin against doxorubicin-induced cardiotoxicity

M Singh, MM Kadhim, A Turki Jalil, SK Oudah… - Cancer Cell …, 2023 - Springer
Purpose Although doxorubicin chemotherapy is commonly applied for treating different
malignant tumors, cardiotoxicity induced by this chemotherapeutic agent restricts its clinical …

Mitochondrial quality control mechanisms as therapeutic targets in doxorubicin-induced cardiotoxicity

L Wu, L Wang, Y Du, Y Zhang, J Ren - Trends in pharmacological sciences, 2023 - cell.com
Doxorubicin (DOX) is a chemotherapeutic drug that is utilized for solid tumors and
hematologic malignancies, but its clinical application is hampered by life-threatening …

Oxidative stress injury in doxorubicin-induced cardiotoxicity

M Songbo, H Lang, C Xinyong, X Bin, Z Ping, S Liang - Toxicology letters, 2019 - Elsevier
Doxorubicin (DOX) is widely used as a broad-spectrum anti-tumor anthracycline to treat
various cancers. The serious adverse effects of DOX on cardiotoxicity limit its clinical …

[HTML][HTML] Preclinical and clinical evidence for the role of resveratrol in the treatment of cardiovascular diseases

BNM Zordoky, IM Robertson, JRB Dyck - Biochimica et Biophysica Acta …, 2015 - Elsevier
Cardiovascular disease is the leading cause of death worldwide. Despite advancements in
diagnosis and treatment of cardiovascular disease, the incidence of cardiovascular disease …

[HTML][HTML] The pharmacology of resveratrol in animals and humans

EJ Park, JM Pezzuto - Biochimica et Biophysica Acta (BBA)-Molecular Basis …, 2015 - Elsevier
In addition to thousands of research papers related to resveratrol (RSV), approximately 300
review articles have been published. Earlier research tended to focus on pharmacological …

Survivorship, version 2.2018, NCCN clinical practice guidelines in oncology

CS Denlinger, T Sanft, KS Baker, G Broderick… - Journal of the National …, 2018 - jnccn.org
The NCCN Guidelines for Survivorship provide screening, evaluation, and treatment
recommendations for common physical and psychosocial consequences of cancer and …

The effect of resveratrol on the cardiovascular system from molecular mechanisms to clinical results

R Gal, L Deres, K Toth, R Halmosi, T Habon - International journal of …, 2021 - mdpi.com
Cardiovascular diseases are the leading causes of death worldwide. The cardioprotective
effects of natural polyphenols such as resveratrol (3, 5, 4-trihydroxystilbene) have been …

Effects of doxorubicin‐induced cardiotoxicity on cardiac mitochondrial dynamics and mitochondrial function: Insights for future interventions

N Osataphan, A Phrommintikul… - Journal of Cellular …, 2020 - Wiley Online Library
Anthracyclines is an effective chemotherapeutic treatment used for many types of cancer.
However, high cumulative dosage of anthracyclines leads to cardiac toxicity and heart …

Exercise training in cancer control and treatment

JF Christensen, C Simonsen… - Comprehensive …, 2011 - Wiley Online Library
Exercise training is playing an increasing role in cancer care, as accumulating evidence
demonstrates that exercise may prevent cancer, control disease progression, interact with …

Sirtuin-3 (SIRT3) protein attenuates doxorubicin-induced oxidative stress and improves mitochondrial respiration in H9c2 cardiomyocytes

KG Cheung, LK Cole, B Xiang, K Chen, X Ma… - Journal of Biological …, 2015 - ASBMB
Doxorubicin (DOX) is a chemotherapeutic agent effective in the treatment of many cancers.
However, cardiac dysfunction caused by DOX limits its clinical use. DOX is believed to be …