Recent applications of synchrotron radiation and neutrons in the study of soft matter

T Narayanan, H Wacklin, O Konovalov… - Crystallography …, 2017 - Taylor & Francis
The broad range of applications of synchrotron and neutron scattering in the investigation of
soft condensed matter is reviewed. Appropriate combinations of these techniques allow …

Biological small-angle neutron scattering: recent results and development

E Mahieu, F Gabel - Acta Crystallographica Section D: Structural …, 2018 - journals.iucr.org
Small-angle neutron scattering (SANS) has increasingly been used by the structural biology
community in recent years to obtain low-resolution information on solubilized …

Saposin lipid nanoparticles: a highly versatile and modular tool for membrane protein research

A Flayhan, HDT Mertens, Y Ural-Blimke, MM Molledo… - Structure, 2018 - cell.com
Saposin-derived lipid nanoparticles (SapNPs) are a new alternative tool for membrane
protein reconstitution. Here we demonstrate the potential and advantages of SapNPs. We …

Biomolecular deuteration for neutron structural biology and dynamics

M Haertlein, M Moulin, JM Devos, V Laux… - Methods in …, 2016 - Elsevier
Neutron scattering studies provide important information in structural biology that is not
accessible using other approaches. The uniqueness of the technique, and its …

Human cystatin C induces the disaggregation process of selected amyloid beta peptides: a structural and kinetic view

A Żyła, A Martel, P Jurczak, A Moliński, A Szymańska… - Scientific Reports, 2023 - nature.com
Neurodegenerative diseases, such as Alzheimer's disease (AD) and various types of
amyloidosis, are incurable; therefore, understanding the mechanisms of amyloid …

Neutron scattering in the biological sciences: progress and prospects

R Ashkar, H Bilheux, H Bordallo, R Briber… - … Section D: Structural …, 2018 - journals.iucr.org
The scattering of neutrons can be used to provide information on the structure and dynamics
of biological systems on multiple length and time scales. Pursuant to a National Science …

Increasing complexity in small-angle X-ray and neutron scattering experiments: from biological membrane mimics to live cells

EF Semeraro, L Marx, MPK Frewein, G Pabst - Soft Matter, 2021 - pubs.rsc.org
Small-angle X-ray and neutron scattering are well-established, non-invasive experimental
techniques to interrogate global structural properties of biological membrane mimicking …

Density matching multi-wavelength analytical ultracentrifugation to measure drug loading of lipid nanoparticle formulations

A Henrickson, JA Kulkarni, J Zaifman, GE Gorbet… - ACS …, 2021 - ACS Publications
Previous work suggested that lipid nanoparticle (LNP) formulations, encapsulating nucleic
acids, display electron-dense morphology when examined by cryogenic-transmission …

Structural modeling of an outer membrane electron conduit from a metal-reducing bacterium suggests electron transfer via periplasmic redox partners

MJ Edwards, GF White, CW Lockwood… - Journal of Biological …, 2018 - ASBMB
Many subsurface microorganisms couple their metabolism to the reduction or oxidation of
extracellular substrates. For example, anaerobic mineral-respiring bacteria can use external …

Invisible detergents for structure determination of membrane proteins by small‐angle neutron scattering

SR Midtgaard, TA Darwish, MC Pedersen… - The FEBS …, 2018 - Wiley Online Library
A novel and generally applicable method for determining structures of membrane proteins in
solution via small‐angle neutron scattering (SANS) is presented. Common detergents for …