G Rinonapoli, V Pace, C Ruggiero, P Ceccarini… - International journal of …, 2021 - mdpi.com
There is a large literature on the relationship between obesity and bone. What we can conclude from this review is that the increase in body weight causes an increase in BMD …
R Eastell, P Szulc - The lancet Diabetes & endocrinology, 2017 - thelancet.com
Bone turnover comprises two processes: the removal of old bone (resorption) and the laying down of new bone (formation). N-terminal propeptide of type I procollagen (PINP) and C …
In an increasingly obese and ageing population, type 2 diabetes (T2DM) and osteoporotic fracture are major public health concerns. Understanding how obesity and type 2 diabetes …
D Ali, M Tencerova, F Figeac, M Kassem… - Frontiers in …, 2022 - frontiersin.org
Osteoporosis is defined as a systemic skeletal disease characterized by decreased bone mass and micro-architectural deterioration leading to increased fracture risk. Osteoporosis …
AG Veldhuis‐Vlug, CJ Rosen - Journal of internal medicine, 2018 - Wiley Online Library
Marrow adipocytes, collectively termed marrow adipose tissue (MAT), reside in the bone marrow in close contact to bone cells and haematopoietic cells. Marrow adipocytes arise …
AL Evans, MA Paggiosi, R Eastell… - Journal of Bone and …, 2015 - academic.oup.com
Obesity is associated with greater areal BMD (aBMD) and is considered protective against hip and vertebral fracture. Despite this, there is a higher prevalence of lower leg and …
W Chemaitilly, Z Li, S Huang, KK Ness… - Journal of Clinical …, 2015 - ascopubs.org
Purpose To estimate the prevalence of and risk factors for growth hormone deficiency (GHD), luteinizing hormone/follicle-stimulating hormone deficiencies (LH/FSHD), thyroid …
Recent evidence demonstrating an increased fracture risk among obese individuals suggests that adipose tissue may negatively impact bone health, challenging the traditional …
SA Shapses, LC Pop, Y Wang - Nutrition research, 2017 - Elsevier
Accumulating evidence supports a complex relationship between adiposity and osteoporosis in overweight/obese individuals, with local interactions and endocrine …