Thiazoles, their benzofused systems, and thiazolidinone derivatives: versatile and promising tools to combat antibiotic resistance

S Cascioferro, B Parrino, D Carbone… - Journal of medicinal …, 2020 - ACS Publications
Thiazoles, their benzofused systems, and thiazolidinone derivatives are widely recognized
as nuclei of great value for obtaining molecules with various biological activities, including …

Aminoacyl-tRNA synthetases: on anti-synthetase syndrome and beyond

AS Galindo-Feria, A Notarnicola, IE Lundberg… - Frontiers in …, 2022 - frontiersin.org
Anti-synthetase syndrome (ASSD) is an autoimmune disease characterized by the presence
of autoantibodies targeting one of several aminoacyl t-RNA synthetases (aaRSs) along with …

[图书][B] Amino acids: biochemistry and nutrition

G Wu - 2021 - taylorfrancis.com
Following its predecessor, the second edition of Amino Acids: Biochemistry and Nutrition
presents exhaustive coverage of amino acids in the nutrition, metabolism and health of …

Metabolomics combined with proteomics provides a novel interpretation of the changes in nonvolatile compounds during white tea processing

Q Chen, J Shi, B Mu, Z Chen, W Dai, Z Lin - Food Chemistry, 2020 - Elsevier
In this study, metabolomics and proteomics were employed to investigate the change
mechanism of nonvolatile compounds during white tea processing. A total of 99 nonvolatile …

Vision, challenges and opportunities for a Plant Cell Atlas

SG Jha, AT Borowsky, BJ Cole, N Fahlgren, A Farmer… - Elife, 2021 - elifesciences.org
With growing populations and pressing environmental problems, future economies will be
increasingly plant-based. Now is the time to reimagine plant science as a critical component …

Impact of imidacloprid exposure on the biochemical responses, transcriptome, gut microbiota and growth performance of the Pacific white shrimp Litopenaeus …

Z Fu, F Han, K Huang, J Zhang, JG Qin, L Chen… - Journal of Hazardous …, 2022 - Elsevier
The widespread use of neonicotinoid insecticides, such as imidacloprid, in agriculture is one
of the key factors for the drop in the survival of invertebrates, including decapod crustaceans …

Roles of aminoacyl-tRNA synthetases in immune regulation and immune diseases

A Nie, B Sun, Z Fu, D Yu - Cell death & disease, 2019 - nature.com
Aminoacyl-tRNA synthetases (ARSs) play a vital role in protein synthesis by linking amino
acids to their cognate transfer RNAs (tRNAs). This typical function has been well recognized …

Targeting aminoacyl tRNA synthetases for antimalarial drug development

SC Xie, MDW Griffin, EA Winzeler… - Annual Review of …, 2023 - annualreviews.org
Infections caused by malaria parasites place an enormous burden on the world's poorest
communities. Breakthrough drugs with novel mechanisms of action are urgently needed. As …

Aminoacyl-tRNA synthetases as valuable targets for antimicrobial drug discovery

L Pang, SD Weeks, A Van Aerschot - International Journal of Molecular …, 2021 - mdpi.com
Aminoacyl-tRNA synthetases (aaRSs) catalyze the esterification of tRNA with a cognate
amino acid and are essential enzymes in all three kingdoms of life. Due to their important …

Mitochondrial DNA transcription and translation: clinical syndromes

V Boczonadi, G Ricci, R Horvath - Essays in biochemistry, 2018 - portlandpress.com
Diagnosing primary mitochondrial diseases is challenging in clinical practice. Although,
defective oxidative phosphorylation (OXPHOS) is the common final pathway, it is unknown …