Synthesis of chalcones derivatives and their biological activities: a review
NAA Elkanzi, H Hrichi, RA Alolayan, W Derafa… - ACS …, 2022 - ACS Publications
Chalcone derivatives are considered valuable species because they possess a
ketoethylenic moiety, CO–CH═ CH–. Due to the presence of a reactive α, β-unsaturated …
ketoethylenic moiety, CO–CH═ CH–. Due to the presence of a reactive α, β-unsaturated …
Design, synthesis, cytotoxic activities, and molecular docking of chalcone hybrids bearing 8-hydroxyquinoline moiety with dual tubulin/EGFR kinase inhibition
MM Amin, GEDA Abuo-Rahma, MSA Shaykoon… - Bioorganic …, 2023 - Elsevier
The present study established thirteen novel 8-hydroxyquinoline/chalcone hybrids 3a–m of
hopeful anticancer activity. According to NCI screening and MTT assay results, compounds …
hopeful anticancer activity. According to NCI screening and MTT assay results, compounds …
Drug candidates for the treatment of Alzheimer's disease: New findings from 2021 and 2022
SL Motebennur, BP Nandeshwarappa… - Drugs and Drug …, 2023 - mdpi.com
Alzheimer's disease (AD), an ongoing neurodegenerative disorder among the elderly, is
signalized by amnesia, progressive deficiency in cognitive roles, and behavioral deformity …
signalized by amnesia, progressive deficiency in cognitive roles, and behavioral deformity …
Photoinduced, Metal-Free Hydroacylation of Aromatic Alkynes for Synthesis of α,β-Unsaturated Ketones via C(sp3)–H Functionalization
Despite the notable advancements made over the past decade in achieving carbon–carbon
bonds by transition-metal-catalyzed cross-coupling processes, metal-free cross-coupling …
bonds by transition-metal-catalyzed cross-coupling processes, metal-free cross-coupling …
Rational design for novel heterocyclic based Donepezil analogs for Alzheimer's disease: an in silico approach
Alzheimer's disease (AD) is a progressive neurodegenerative disease and has devastating
impacts on the elderly population. During the last two decades, there has been a significant …
impacts on the elderly population. During the last two decades, there has been a significant …
An Overview of Synthesis and Applications of Chalcone Derivatives
H Ahmed, AA Ahmed, A Al-Ani, J Jebali… - Al-Nahrain Journal of …, 2024 - anjs.edu.iq
Chalcone and its derivatives have attracted great attention because of a wide range of
biological activities such as, antimicrobial, anticancer, antioxidant, anti-anthelmintic, anti …
biological activities such as, antimicrobial, anticancer, antioxidant, anti-anthelmintic, anti …
Synthesis and characterization of the aminated nano-zeolite: A green heterogeneous nanocatalyst for the synthesis of valuable organic compounds
K Rabiei, F Najafi - Journal of Particle Science and Technology, 2022 - jpst.irost.ir
In this study, natural surface-modified nano-clinoptilolite, NCP@ SiO3Pr (CH2) 6N4, was
synthesized and fully characterized using various analytical techniques, including FT-IR …
synthesized and fully characterized using various analytical techniques, including FT-IR …