Myxobacteria are fascinating and complex microbes. They prey upon other members of the
soil microbiome by secreting antimicrobial proteins and metabolites, and will undergo …

The bacterial chromosome is compacted in a manner optimal for DNA transactions to occur.
The degree of compaction results from the level of DNA-supercoiling and the presence of …

Bacterial genome organization is primarily driven by chromosomal replication from a single
origin of replication. However, chromosomal rearrangements, which can disrupt such …

In Bacteria, chromosome replication starts at a single origin of replication and proceeds on
both replichores. Due to its asymmetric nature, replication influences chromosome structure …

Inversions are a major contributor to structural genome evolution in prokaryotes. Here, using
a novel alignment-based method, we systematically compare 1,651 bacterial and 98 …

DNA supercoiling and nucleoid-associated proteins (NAPs) are two of the factors that
govern the architecture of the bacterial genome, influencing the expression of the genetic …

Using phylogenomic and gene compositional analyses, five highly conserved gene families
have been detected in the core genome of the phylogenetically coherent genus …

The bacterium Escherichia coli can initiate replication in the absence of the replication
initiator protein DnaA and/or the canonical origin of replication oriC in a ΔrnhA background …

The structural arrangements of bacterial chromosomes vary widely between closely related
species and can result in significant phenotypic outcomes. The appearance of large-scale …

The bacterium E. coli can replicate its DNA in the absence of the replication initiator protein
DnaA and/or the canonical origin of replication oriC in a ΔrnhA background. This often …