Gut microbiota dysbiosis is associated with altered tryptophan metabolism and dysregulated inflammatory response in COVID-19

M Essex, B Millet Pascual-Leone, U Löber… - npj Biofilms and …, 2024 - nature.com
The clinical course of COVID-19 is variable and often unpredictable. To test the hypothesis
that disease progression and inflammatory responses associate with alterations in the …

The role of the gut microbiota in regulating responses to vaccination: current knowledge and future directions

C Rossouw, FJ Ryan, DJ Lynn - The FEBS Journal, 2024 - Wiley Online Library
Antigen‐specific B and T cell responses play a critical role in vaccine‐mediated protection
against infectious diseases, but these responses are highly variable between individuals …

Influenza and the gut microbiota: A hidden therapeutic link

C Luo, Y Yang, C Jiang, A Lv, W Zuo, Y Ye, J Ke - Heliyon, 2024 - cell.com
Background The extensive community of gut microbiota significantly influences various
biological functions throughout the body, making its characterization a focal point in …

[HTML][HTML] Gut microbiota wellbeing index predicts overall health in a cohort of 1000 infants

B Hickman, A Salonen, AJ Ponsero, R Jokela… - Nature …, 2024 - nature.com
The human gut microbiota is central in regulating all facets of host physiology, and in early
life it is thought to influence the host's immune system and metabolism, affecting long-term …

Orsay virus infection increases Caenorhabditis elegans resistance to heat-shock

VG Castiglioni, SF Elena - Biology Letters, 2024 - royalsocietypublishing.org
The heat-shock response plays a key role in the immune defence against viruses across
various organisms. Studies on model organisms have shown that inducing this response …

Farnesoid X receptor enhances epithelial ACE2 expression and inhibits virally induced IL-6 secretion: implications for intestinal symptoms of SARS-CoV-2

JS Smyth, JK Truong, A Rao, R Lin… - American Journal …, 2023 - journals.physiology.org
Intestinal inflammation and diarrhea are often associated with SARS-CoV-2 infection. The
angiotensin converting enzyme 2 (ACE2) receptor plays a key role in SARS-CoV-2 …

Prebiotic inulin ameliorates SARS-CoV-2 infection in hamsters by modulating the gut microbiome

I Song, J Yang, M Saito, T Hartanto, Y Nakayama… - npj Science of …, 2024 - nature.com
Current treatment options for COVID-19 are limited, with many antivirals and
immunomodulators restricted to the most severe cases and preventative care limited to …

Metabolic immaturity and breastmilk bile acid metabolites are central determinants of heightened newborn vulnerability to norovirus diarrhea

AM Peiper, JM Aparicio, Z Hu, L Phophi, EW Helm… - Cell Host & Microbe, 2024 - cell.com
The pathogenic outcome of enteric virus infections is governed by a complex interplay
between the virus, intestinal microbiota, and host immune factors, with metabolites serving …

Effect of varying temperature increases on the microbial community of Pleistocene and Holocene permafrost

LAC Nguyen, G Iwahana, S Fukuda, K Nakazawa… - Polar Science, 2024 - Elsevier
The total area covered by permafrost has been continually decreasing over the past
decades. This study investigates the effect of various temperature increases on the …

Comparative Analysis of COVID-19 Responses in Japan and Africa: Diet, Phytochemicals, Vitamin D, and Gut Microbiota in Reducing Mortality-A Systematic Review …

K Santa, R Tamaki, K Watanabe, I Nagaoka - Frontiers in Nutrition, 2024 - frontiersin.org
Background: As the novel coronavirus disease 2019 (COVID-19) pandemic subsides, the
clinical sequelae are becoming more problematic. Interestingly, the statistical data indicate …