In recent years, and even more since its legalization in several jurisdictions, cannabis and
the endocannabinoid system have received an increasing amount of interest related to their …

Silybum marianum (SM), a well-known plant used as both a medicine and a food, has been
widely used to treat various diseases, especially hepatic diseases. The seeds and fruits of …

Silymarin contains a group of closely-related flavonolignan compounds including silibinin,
and is extracted from Silybum marianum species, also called milk thistle. Silymarin has been …

The flavonoid silymarin extracted from the seeds of Sylibum marianum is a mixture of 6
flavolignan isomers. The 3 more important isomers are silybin (or silibinin), silydianin, and …

Medicinal plants are considered the reservoir of diverse therapeutic agents and have been
traditionally employed worldwide to heal various ailments for several decades. Silymarin is a …

Benzo [a] pyrene (B [a] P), a polycyclic aromatic hydrocarbon, is a group 1 carcinogen that
introduces mutagenic DNA adducts into the genome. In this study, we investigated the …

Abstract Roundabout guidance receptor 2 (Robo2) is closely related to malignant tumors
such as pancreatic cancer and liver fibrosis, but there is no relevant research on the role of …

Gliomas represent the most common primary Central Nervous System (CNS) tumors,
characterized by increased heterogeneity, dysregulated intracellular signaling, extremely …

Silybum marianum seeds contain a family of flavonolignans which can regulate cancer cell
proliferation and apoptosis. However, research has rarely focused on the effect of S …

Benzo [a] pyrene (B [a] P), a polycyclic aromatic hydrocarbon, poses a significant threat to
human health as an increasingly prevalent environmental and foodborne pollutant. Our …