Kidney disease is a global health problem with high mortality and socioeconomic burden,
including acute kidney injury (AKI), chronic kidney disease (CKD), diabetic nephropathy …

Glomerulonephritis is traditionally considered to result from the invasion of the kidney by
autoantibodies and immune complexes from the circulation or following their formation in …

Inflammation has an integral role in the pathophysiology of AKI. We investigated the
associations of two biomarkers of inflammation, plasma IL-6 and IL-10, with AKI and …

Simple Summary Increased stress is often observed in patients with kidney diseases,
contributing to renal injury progression. Flavonoids are naturally occurring plant compounds …

Kidneys are critical target organs of COVID-19, but susceptibility and responses to infection
remain poorly understood. Here, we combine SARS-CoV-2 variants with genome-edited …

Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by
autoantibody production and multiple organ damage. Toll-like receptor 7 (TLR7), an innate …

Doxorubicin (DOX) is an anti-neoplastic therapy, but its use is limited by its deleterious toxic
effects including nephrotoxicity and cardiotoxicity. This work aimed at assessing the …

Background As children progress to higher stages of AKI, the risk for adverse outcomes
dramatically increases. No reliable methods exist to predict AKI progression in hospitalized …

Defective α-galactosidase A (AGAL/GLA) due to missense or nonsense mutations in the
GLA gene results in accumulation of the glycosphingolipids globotriaosylceramide (Gb3) …

Background: As a part of natural disease progression, acute kidney injury (AKI) can develop
into chronic kidney disease via renal fibrosis and inflammation. LTBP4 (latent transforming …