Posterior corneoscleral limbus: Architecture, stem cells, and clinical implications

GHF Yam, S Pi, Y Du, JS Mehta - Progress in Retinal and Eye Research, 2023 - Elsevier
The limbus is a transition from the cornea to conjunctiva and sclera. In human eyes, this thin
strip has a rich variation of tissue structures and composition, typifying a change from scleral …

Wave-based optical coherence elastography: the 10-year perspective

F Zvietcovich, KV Larin - Progress in Biomedical Engineering, 2022 - iopscience.iop.org
After ten years of progress and innovation, optical coherence elastography (OCE) based on
the propagation of mechanical waves has become one of the major and the most studied …

Multifocal acoustic radiation force-based reverberant optical coherence elastography for evaluation of ocular globe biomechanical properties

T Mekonnen, C Zevallos-Delgado… - Journal of …, 2023 - spiedigitallibrary.org
Significance Quantifying the biomechanical properties of the whole eye globe can provide a
comprehensive understanding of the interactions among interconnected ocular components …

In vivo assessment of corneal biomechanics under a localized cross-linking treatment using confocal air-coupled optical coherence elastography

F Zvietcovich, A Nair, M Singh, SR Aglyamov… - Biomedical optics …, 2022 - opg.optica.org
The localized application of the riboflavin/UV-A collagen cross-linking (UV-CXL) corneal
treatment has been proposed to concentrate the stiffening process only in the compromised …

Revealing regional variations in scleral shear modulus in a rabbit eye model using multi-directional ultrasound optical coherence elastography

L Villegas, F Zvietcovich, S Marcos, JS Birkenfeld - Scientific reports, 2024 - nature.com
The mechanical properties of the sclera play a critical role in supporting the ocular structure
and maintaining its shape. However, non-invasive measurements to quantify scleral …

Acoustic radiation force optical coherence elastography: A preliminary study on biomechanical properties of trabecular meshwork

S Ai, Y Zhang, G Shi, Y Wang, G Liu… - Journal of …, 2023 - Wiley Online Library
Evaluating biomechanical properties of trabecular meshwork (TM) is of great significance for
understanding the mechanism of aqueous humor circulation and its relationship to some …

Estimation of scleral mechanical properties from air-puff optical coherence tomography

D Bronte-Ciriza, JS Birkenfeld, A de la Hoz… - Biomedical Optics …, 2021 - opg.optica.org
We introduce a method to estimate the biomechanical properties of the porcine sclera in
intact eye globes ex vivo, using optical coherence tomography that is coupled with an air …

In situ measurement of the stiffness increase in the posterior sclera after UV-riboflavin crosslinking by optical coherence elastography

M Vinas-Pena, X Feng, G Li, SH Yun - Biomedical optics express, 2022 - opg.optica.org
Scleral crosslinking may provide a way to prevent or treat myopia by stiffening scleral
tissues. The ability to measure the stiffness of scleral tissues in situ pre and post scleral …

Hyaluronan modulates the biomechanical properties of the cornea

X Lin, T Mekonnen, S Verma… - … & Visual Science, 2022 - iovs.arvojournals.org
Purpose: Hyaluronan (HA) is a major constituent of the extracellular matrix (ECM) that has
high viscosity and is essential for maintaining tissue hydration. In the cornea, HA is enriched …

Dynamic evaluation of corneal cross-linking and osmotic diffusion effects using optical coherence elastography

M Frigelli, P Büchler, S Kling - Scientific reports, 2024 - nature.com
Dynamic deformation events induced by osmosis or photochemical stiffening substantially
influence geometrical and mechanical assessments in post-mortem corneas, therefore need …