INTRODUCTION The epidemic of substance use disorders and drug overdose deaths is a
growing public health crisis in the United States. Every day, 174 people die from drug …

Background Hospitalizations due to medical and surgical complications of substance use
disorder (SUD) are rising. Most hospitals lack systems to treat SUD, and most people with …

Better opioid prescribing practices, promoting effective opioid use disorder treatment,
improving naloxone access, and enhancing public health surveillance are strategies central …

Background In the midst of an opioid epidemic, health care workers are encountering an
increasing number of patients who have opioid use disorder in addition to complex social …

Importance Timely initiation and referral to treatment for patients with opioid use disorder
seen in the emergency department is associated with reduced mortality. It is not known how …

Background The opioid epidemic in the United States remains a critically important public
health issue and continues to worsen. While healthcare data and outcomes are commonly …

Widely-prescribed prodrug opioids (eg, hydrocodone) require conversion by liver enzyme
CYP-2D6 to exert their analgesic effects. The most commonly prescribed antidepressant …

Background Understanding more about circumstances in which patients receive an opioid
use disorder (OUD) diagnosis might illuminate opportunities for intervention and ultimately …

Fatal drug overdoses among pregnant and postpartum individuals have risen dramatically
over the past 10 years. Trends in and characteristics of nonfatal drug overdoses in this …

Introduction US hospital discharges for opioid overdose increased substantially during the
past two decades. This brief report describes 90-day readmissions among patients …