The central noradrenergic neurone, like the peripheral sympathetic neurone, is
characterized by a diffusely arborizing terminal axonal network. The central neurones …

In dentistry, bruxism is traditionally considered an oral parafunction characterized by
involuntary grinding and clenching of the teeth. 1, 2 Although this definition describes the …

Normal waking is associated with neuronal activity in several chemically defined ascending
arousal systems. These include monoaminergic neurons in the brainstem and posterior …

Uyku sağlık ve yaşamımızın iyi bir şekilde devamı için önemli bir role sahiptir. Kaliteli uyku
zihinsel sağlığımızı, fiziksel sağlığımızı, hayat kalitemizı korumamıza yardım eder ve …

Pregabalin is a specific ligand of the alpha 2-delta (α 2-δ) auxiliary subunit of voltage-gated
calcium channels. A growing body of evidence from studies of anxiety and pain indicate that …

Ever since the discovery of rapid eye movement sleep (REMS), studies have been
undertaken to understand its necessity, function and mechanism of action on normal …

Many neurodegenerative disorders are associated with rapid eye movement sleep (REMS)
loss; however, the mechanism was unknown. As REMS loss elevates noradrenaline (NA) …

Abstract Study Objective: Clonidine disrupts the NREM/REM sleep cycle and reduces the
incidence of rhythmic masticatory muscle activity (RMMA) characteristic of sleep bruxism …

Rapid eye movement sleep (REMS) favors brain development and memory, while it is
decreased in neurodegenerative diseases. REMS deprivation (REMSD) affects several …

Objective To evaluate the predictive value of disturbed sleep on the ability of pregabalin to
reduce pain associated with diabetic peripheral neuropathy (DPN) and post-herpetic …