This paper introduces a new construct, the 'pivotal mental state', which is defined as a hyper-
plastic state aiding rapid and deep learning that can mediate psychological transformation …

Background We consider the evidence for the proposition that the early phase of psychosis
(including the period of untreated psychosis) is a critical period'in which (a) long-term …

Intervention in the prodromal phase of schizophrenia and related psychoses may result in
attenuation, delay or even prevention of the onset of psychosis in some individuals …

▪ Abstract A combination of genetic susceptibility and environmental perturbations appear to
be necessary for the expression of schizophrenia. In addition, the pathogenesis of the …

This article describes the theoretical background, origins, and development of a new clinical
service for intervention in the putatively prodromal phase of schizophrenia and other …

Early intervention at the onset of psychotic disorders is a highly attractive theoretical notion
that is receiving increasing international interest. In practical terms, it amounts to first …

Objective: This study aimed to describe in detail, using a retrospective approach, the
prodromal symptoms in first-episode psychosis patients. This initial prodrome, the period of …

Schizophrenia and mania have a number of symptoms and epidemiological characteristics
in common, and both respond to dopamine blockade. Family, twin and molecular genetic …

Individuals with schizophrenia experience problems in the perception of emotional material;
however, the specificity, extent, and nature of the deficits are unclear. Facial affect and …

OBJECTIVE: This research examined social functioning in childhood and adolescence
among patients with schizophrenia and patients with bipolar disorder compared with healthy …