Breast cancer remains to be a dreadful disease even with several advancements in
radiation and chemotherapies, owing to the drug resistance and tumor relapse caused by …

The nonsteroidal anti‐inflammatory agent aspirin is widely used for preventing and treating
cardiovascular and cerebrovascular diseases. In addition, epidemiologic evidences reveal …

In breast tumors, activation of the nuclear factor κB (NFκB) pathway promotes survival,
migration, invasion, angiogenesis, stem cell-like properties, and resistance to therapy—all …

Estrogen receptor β (ERβ) plays critical roles in thyroid cancer progression. However, its role
in thyroid cancer stem cell maintenance remains elusive. Here, we report that ERβ is …

Breast cancer stem cells (BCSCs) are the minor population of breast cancer (BC) cells that
exhibit several phenotypes such as migration, invasion, self-renewal, and chemotherapy as …

Abstract Series of piperidone-salicylate conjugates were synthesized through the reaction of
3E, 5E-bis (arylidene)-4-piperidones with the appropriate acid chloride of acetylsalicylate in …

The poor survival and prognosis of individuals with cancer are often attributed to tumour
relapse and metastasis, which may be due to the presence of cancer stem cells (CSCs) …

Breast cancers with estrogen receptor (ER) expressions account for the majority of all
clinical cases. Due to hormone therapy with tamoxifen, prognoses of patients with ER …

Stimulus-responsive cleavage reactions have found broad use to direct drug release at a
particular target disease area. Increased levels of reactive oxygen species (ROS) have been …

Aspirin is a widely used medicine for a variety of indications. It is unique amongst non-
steroidal anti-inflammatory drugs (NSAIDs) in that it causes irreversible acetylation of COX …