Benzothiazole-based fluorescent probes are formed by decorating benzothiazole fluorophore with a small chemical fragment capable of detecting a particular biological …
X Fang, Y Zheng, Y Duan, Y Liu, W Zhong - Analytical chemistry, 2018 - ACS Publications
Significant improvements in disease management have been achieved in the past few decades. Using cancer as an example, survival rates have increased dramatically in …
W Long, BX Zheng, Y Li, XH Huang, DM Lin… - Nucleic acids …, 2022 - academic.oup.com
DNA G4-structures from human c-MYC promoter and telomere are considered as important drug targets; however, the developing of small-molecule-based fluorescent binding ligands …
AR Duarte, E Cadoni, AS Ressurreição… - …, 2018 - Wiley Online Library
Guanine‐rich nucleic acid sequences able to form four‐stranded structures (G‐ quadruplexes, G4) play key cellular regulatory roles and are considered as promising drug …
Over the past decade, appreciation of the roles of G-quadruplex (G4) structures in cellular regulation and maintenance has rapidly grown, making the establishment of robust methods …
O Suss, L Motiei, D Margulies - Molecules, 2021 - mdpi.com
Fluorescent sensing of biomolecules has served as a revolutionary tool for studying and better understanding various biological systems. Therefore, it has become increasingly …
V Grande, F Doria, M Freccero… - Angewandte Chemie, 2017 - Wiley Online Library
Abstract G‐quadruplexes (G4s) are peculiar DNA or RNA tertiary structures that are involved in the regulation of many biological events within mammalian cells, bacteria, and viruses …
BX Zheng, J Yu, W Long, KH Chan… - Chemical …, 2023 - pubs.rsc.org
The formation of G-quadruplex structures (G4s) in vitro from guanine (G)-rich nucleic acid sequences of DNA and RNA stabilized with monovalent cations, typically K+ and Na+, under …
G-quadruplexes have gained prominence over the past two decades for their role in gene regulation, control of anti-tumour activity and ageing. The physiological relevance and …