Type 2 diabetes

S Chatterjee, K Khunti, MJ Davies - The lancet, 2017 - thelancet.com
Summary 415 million people live with diabetes worldwide, and an estimated 193 million
people have undiagnosed diabetes. Type 2 diabetes accounts for more than 90% of patients …

The pharmacology and therapeutic applications of monoclonal antibodies

MS Castelli, P McGonigle… - Pharmacology research & …, 2019 - Wiley Online Library
Monoclonal antibodies (mAbs) have emerged as a major class of therapeutic agents on the
market. To date, approximately 80 mAbs have been granted marketing approval. In 2018, 12 …

Adherence to diabetes medication: a systematic review

I Krass, P Schieback, T Dhippayom - Diabetic Medicine, 2015 - Wiley Online Library
Aims To investigate the extent of and factors associated with adherence to Type 2 diabetes
medication. Methods The CINAHL, Embase, International Pharmaceutical Abstracts …

Nonadherence with antipsychotic medication in schizophrenia: challenges and management strategies

PM Haddad, C Brain, J Scott - Patient related outcome measures, 2014 - Taylor & Francis
Nonadherence with medication occurs in all chronic medical disorders. It is a particular
challenge in schizophrenia due to the illness's association with social isolation, stigma, and …

Determinants of adherence to diabetes treatment: 糖尿病治疗依从性的决定因素

AT Larkin, C Hoffman, A Stevens, A Douglas… - Journal of …, 2015 - Wiley Online Library
摘要背景: 在糖尿病的管理中了解与改善用药依从性至关重要. 高依从性的糖尿病治疗方法可以
改善血糖控制并且预防并发症的发生. 当前这项研究的目的是评估影响糖尿病用药依从性的各种 …

Glucagon‐like peptide‐1 receptor agonists in type 2 diabetes treatment: are they all the same?

R Gentilella, V Pechtner, A Corcos… - … research and reviews, 2019 - Wiley Online Library
Summary Glucagon‐like peptide‐1 (GLP‐1) receptor agonists (RAs) are an important class
of drugs with a well‐established efficacy and safety profile in patients with type 2 diabetes …

Identification of barriers to insulin therapy and approaches to overcoming them

D Russell‐Jones, F Pouwer… - Diabetes, Obesity and …, 2018 - Wiley Online Library
Poor glycaemic control in type 2 diabetes (T2D) is a global problem despite the availability
of numerous glucose‐lowering therapies and clear guidelines for T2D management …

Pharmacokinetic and pharmacodynamic properties of the novel basal insulin Fc (insulin efsitora alfa), an insulin fusion protein in development for once‐weekly dosing …

T Heise, J Chien, JM Beals, C Benson… - Diabetes, Obesity …, 2023 - Wiley Online Library
Aim To assess the safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) of
basal insulin Fc (BIF; LY3209590), a fusion protein combining a novel single‐chain insulin …

Safety and efficacy of once-weekly basal insulin Fc in people with type 2 diabetes previously treated with basal insulin: a multicentre, open-label, randomised, phase 2 …

J Frias, J Chien, Q Zhang, E Chigutsa… - The Lancet Diabetes & …, 2023 - thelancet.com
Background The burden of daily basal insulins often causes hesitancy and delays in the
initiation of insulin therapy. Basal insulin Fc (BIF, insulin efsitora alfa), designed for once …

[HTML][HTML] Clinical inertia and its impact on treatment intensification in people with type 2 diabetes mellitus

G Reach, V Pechtner, R Gentilella, A Corcos… - Diabetes & …, 2017 - Elsevier
Many people with type 2 diabetes mellitus (T2DM) fail to achieve glycaemic control promptly
after diagnosis and do not receive timely treatment intensification. This may be in part due to …