Purpose Bacillus anthracis infection (anthrax) can be highly lethal. Two recent outbreaks
related to contaminated mail in the USA and heroin in the UK and Europe and its potential …

Moxifloxacin (Avelox®) is a fluoroquinolone antibacterial with a methoxy group in the C-8
position and a bulky C-7 side chain. Moxifloxacin is approved for use in the treatment of …

The lantibiotic nisin inhibits growth of vegetative Gram-positive bacteria by binding to lipid II,
which disrupts cell wall biosynthesis and facilitates pore formation. Nisin also inhibits the …

Amoxicillin is recommended for anthrax prevention in pregnancy. The objective of this study
was to evaluate the pharmacokinetics of amoxicillin during pregnancy and postpartum (PP) …

Immunization with BioThrax®(Anthrax Vaccine Adsorbed) is a safe and effective means of
preventing anthrax. Animal studies have demonstrated that the addition of CpG DNA …

Cationic Host Defense Peptides (HDP, also known as antimicrobial peptides) are crucial
components of the innate immune system and possess broad-spectrum antibacterial …

Anthrax is an infectious disease caused by toxigenic strains of the Gram-positive Bacillus
anthracis.[1] If inhaled, B. anthracis spores rapidly reach the regional lymphonodes of the …

Objectives: The aim of this study was to investigate in vitro the post-antibiotic effect (PAE) of
19 antibacterial agents against two strains of Bacillus anthracis (ST-1 and Sterne strains) …

The increased awareness of the central role of RNA has led to realization that RNA, as
structural and functional information accumulation, is also drug target to small molecular …

Bacillus anthracis is a Gram-positive spore-forming bacterium that causes anthrax. With the
increased threat of anthrax in biowarfare, there is an urgent need to characterize new …