The microbiome of the upper respiratory tract in health and disease

C Kumpitsch, K Koskinen, V Schöpf… - BMC biology, 2019 - Springer
The human upper respiratory tract (URT) offers a variety of niches for microbial colonization.
Local microbial communities are shaped by the different characteristics of the specific …

The lung microbiome: progress and promise

SA Whiteside, JE McGinniss… - The Journal of Clinical …, 2021 - Am Soc Clin Investig
The healthy lung was long thought of as sterile, but recent advances using molecular
sequencing approaches have detected bacteria at low levels. Healthy lung bacteria largely …

[HTML][HTML] MicrobiotaProcess: A comprehensive R package for deep mining microbiome

S Xu, L Zhan, W Tang, Q Wang, Z Dai, L Zhou, T Feng… - The Innovation, 2023 - cell.com
The data output from microbiome research is growing at an accelerating rate, yet mining the
data quickly and efficiently remains difficult. There is still a lack of an effective data structure …

Multigroup analysis of compositions of microbiomes with covariate adjustments and repeated measures

H Lin, SD Peddada - Nature Methods, 2024 - nature.com
Microbiome differential abundance analysis methods for two groups are well-established in
the literature. However, many microbiome studies involve more than two groups, sometimes …

Role of oral microbiome signatures in diagnosis and prognosis of oral cancer

I Chattopadhyay, M Verma… - Technology in cancer …, 2019 - journals.sagepub.com
Despite advancement in cancer treatment, oral cancer has a poor prognosis and is often
detected at late stage. To overcome these challenges, investigators should search for early …

Stress and stability: applying the Anna Karenina principle to animal microbiomes

JR Zaneveld, R McMinds, R Vega Thurber - Nature microbiology, 2017 - nature.com
All animals studied to date are associated with symbiotic communities of microorganisms.
These animal microbiotas often play important roles in normal physiological function and …

[HTML][HTML] The microbiota of the respiratory tract: gatekeeper to respiratory health

WH Man, WAA de Steenhuijsen Piters… - Nature Reviews …, 2017 - nature.com
The respiratory tract is a complex organ system that is responsible for the exchange of
oxygen and carbon dioxide. The human respiratory tract spans from the nostrils to the lung …

Role of probiotics to combat viral infections with emphasis on COVID-19

A Sundararaman, M Ray, PV Ravindra… - Applied microbiology and …, 2020 - Springer
Interspecies transmissions of viruses between animals and humans may result in
unpredictable pathogenic potential and new transmissible diseases. This mechanism has …

Smoking and microbiome in oral, airway, gut and some systemic diseases

C Huang, G Shi - Journal of translational medicine, 2019 - Springer
The human microbiome harbors a diverse array of microbes which establishes a mutually
beneficial relation with the host in healthy conditions, however, the dynamic homeostasis is …

Lung microbiome: new insights into the pathogenesis of respiratory diseases

R Li, J Li, X Zhou - Signal transduction and targeted therapy, 2024 - nature.com
The lungs were long thought to be sterile until technical advances uncovered the presence
of the lung microbial community. The microbiome of healthy lungs is mainly derived from the …