Quercetin and related chromenone derivatives as monoamine oxidase inhibitors: targeting neurological and mental disorders
Monoamine oxidase inhibitions are considered as important targets for the treatment of
depression, anxiety, and neurodegenerative disorders, including Alzheimer's and …
depression, anxiety, and neurodegenerative disorders, including Alzheimer's and …
Biological Evaluation, DFT Calculations and Molecular Docking Studies on the Antidepressant and Cytotoxicity Activities of Cycas pectinata Buch.-Ham. Compounds
Cycas pectinata Buch.-Ham. is commonly used in folk medicine against various disorders.
The present study investigated the antidepressant and cytotoxicity activity of methanol …
The present study investigated the antidepressant and cytotoxicity activity of methanol …
[HTML][HTML] Chemical profiles and pharmacological insights of Anisomeles indica Kuntze: An experimental chemico-biological interaction
Anisomeles indica (L.) Kuntze is an ethnomedicinally important plant that has long been
used in traditional medicine to treat a variety of ailments, including dyspepsia, abdominal …
used in traditional medicine to treat a variety of ailments, including dyspepsia, abdominal …
[HTML][HTML] Review on potential phytocompounds in drug development for Parkinson disease: a pharmacoinformatic approach
S Vijayakumar, S Prabhu, S Rajalakhsmi… - Informatics in Medicine …, 2016 - Elsevier
Parkinson's disease (PD) is caused by human physiological function and is ranked as the
second most common neurodegenerative disorder. One of the prominent therapies currently …
second most common neurodegenerative disorder. One of the prominent therapies currently …
3D-QSAR and in-silico studies of natural products and related derivatives as monoamine oxidase inhibitors
Background: The computational development of human monoamine oxidase (MAO)
inhibitors led to advancement in drug design and the treatment of many neurodegenerative …
inhibitors led to advancement in drug design and the treatment of many neurodegenerative …
In silico study to identify new monoamine oxidase type a (MAO-A) selective inhibitors from natural source by virtual screening and molecular dynamics simulation
Neurological (such as stroke, Alzheimer's, Parkinson's, epilepsy) and neuropsychiatric (such
as autism, migraine, depression, anxiety, stress) disorders continue to be on rising every …
as autism, migraine, depression, anxiety, stress) disorders continue to be on rising every …
Docking-related survey on natural-product-based new monoamine oxidase inhibitors and their therapeutic potential
Background: This is an exciting period for research on monoamine oxidase and its effects on
central nervous system. As the current hitting-one-target, therapeutic strategy has become …
central nervous system. As the current hitting-one-target, therapeutic strategy has become …
[HTML][HTML] Anxiolytic, anti-nociceptive and body weight reducing effects of L-lysine in rats: Relationship with brain serotonin an In-Vivo and In-Silico study
Abstract L-lysine (L-lys) had long been comprehended as an essential amino acid for
humans. There were reports that the absence or inadequate availability of L-lys in the diet …
humans. There were reports that the absence or inadequate availability of L-lys in the diet …
[PDF][PDF] Antidepressant-like effect of natural compounds of Melissa officinalis L.
DŞ Manolescu, G Uță, S Avram - Romanian Journal of Biophysics, 2022 - rjb.ro
Globally the most common mental disorder is depression. Depression therapy is based on
medication supported by psychotherapy or neurofeedback. Drugs that treat or ameliorate the …
medication supported by psychotherapy or neurofeedback. Drugs that treat or ameliorate the …
Synthesis of Chromen-1-phenylpropan-1-one Derivatives and their Antidepressant/Anticonvulsant Activities
SS Zhang, WH Liu, ZW He, QW Tan… - Letters in Drug Design …, 2021 - ingentaconnect.com
Background: Coumarin and chalcone are important secondary plant metabolites that exhibit
a range of biological activities. Accordingly, the synthetic derivatives and analogs of these …
a range of biological activities. Accordingly, the synthetic derivatives and analogs of these …