Globally, prostate cancer (PCa) is regarded as a challenging health issue, and the number
of PCa patients continues to rise despite the availability of effective treatments in recent …

Glioblastoma multiforme (GBM), a greatly aggressive malignancy of the brain, is correlated
with a poor prognosis and low rate of survival. Up to now, chemotherapy and radiation …

Glioma and cerebral ischemic stroke are two major events that lead to patient death
worldwide. Although these conditions have different physiological incidences,~ 10% of …

Rheumatoid arthritis (RA) is a kind of chronic autoimmune disease. The existing therapies
encountered several challenges. Therefore, continued novel anti-RA drug discovery …

Demethoxycurcumin (DMC) is a curcumin analogue with better stability and higher aqueous
solubility than curcumin after oral ingestion and has the potential to treat diverse cancers …

Esophageal squamous cell carcinoma (ESCC), a major histologic type of esophageal
cancer, is one of the frequent causes of cancer-related death worldwide …

Nasopharyngeal carcinoma (NPC) is a malignant tumor originating from the superior
mucosal epithelium of the nasopharynx. However, effective therapies for NPC are still …

Hainanolide (HN) is a norditerpenoid metabolite extract from Cephalotaxus fortunei Hook. f.
C. fortunei Hook. f. is renowned for the active alkaloids, such as harringtonine (HT) and …

In this research paper, we report the design and synthesis of novel substituted biscarbazole
derivatives which were characterized by 1 H and 13 C NMR, high resolution mass …

Curcumae Rhizoma (CR) and vinegar processed Curcumae Rhizoma (PCR) are common
medicinal materials widely used in clinical practice in China. There are sliced CR (SCR) and …