Depression represents a global mental health concern, and disproportionally affects women
as they are twice more likely to be diagnosed than men. In this review, we provide a …

Mutual regulation and balance between the endocrine and immune systems facilitate an
organism's stress response and are impaired following chronic stress or prolonged immune …

Recent reports have demonstrated that lipopolysaccharide (LPS)-induced depressive-like
behaviour is mediated via NMDA receptor. In this study, we further investigated the role of …

Adverse maternal environment (AME) and high‐fat diet in early childhood increase the risk
of cognitive impairment and depression later in life. Cognitive impairment associates with …

Objective We performed ITRAQ assay of the ovarian tissues from 4 mice with cisplatin-
induced POI and 4 control mice, and identified FKBP4 as a significantly down-regulated …

Background Curcumae Radix (CR), derived from the dry roots of Curcuma longa L., family
Zingiberaceae, is widely used to treat depression. However, the ingredients and …

miR-483-5p通过靶向FKBP4加重顺铂诱导的小鼠卵巢损伤- PMC Back to Top Skip to main
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Inflammation plays a critical role in pathogenesis of depression and can affect the
hypothalamic-pituitary-adrenal axis activity. Accordingly, in this study we investigated the …

The Hsp90 chaperone is known to interact with a diverse array of client proteins. However,
in every case examined, Hsp90 is also accompanied by a single or several co-chaperone …

Mitochondrial dysfunction can result from the interplay between elevated inflammatory
markers and alterations in hypothalamic–pituitary–adrenal (HPA) axis, and can contribute to …