Osteotropic nanoscale drug delivery systems based on small molecule bone-targeting moieties

EJ Carbone, K Rajpura, BN Allen, E Cheng… - … , Biology and Medicine, 2017 - Elsevier
Bone-targeted drug delivery is an active research area because successful clinical
applications of this technology can significantly advance the treatment of bone injuries and …

Design and characterization of paclitaxel-loaded polymeric nanoparticles decorated with trastuzumab for the effective treatment of breast cancer

M Sakhi, A Khan, Z Iqbal, I Khan, A Raza… - Frontiers in …, 2022 - frontiersin.org
The aim of the study was to design and formulate an antibody-mediated targeted,
biodegradable polymeric drug delivery system releasing drug in a controlled manner to …

Role of colloidal drug delivery carriers in taxane-mediated chemotherapy: a review

P Kumar, K Raza, L Kaushik, R Malik… - Current …, 2016 - ingentaconnect.com
Chemotherapy is one of the most frequently employed and reliable treatment options for the
management of a variety of cancers. Taxanes (paclitaxel, docetaxel and cabazitaxel) are …

The tumor-targeting core–shell structured DTX-loaded PLGA@ Au nanoparticles for chemo-photothermal therapy and X-ray imaging

Y Hao, B Zhang, C Zheng, R Ji, X Ren, F Guo… - Journal of Controlled …, 2015 - Elsevier
In this study, an organic–inorganic hybrid nanocomposite was synthesized by deposition of
Au onto the surface of docetaxel (DTX)-loaded poly (lactide-co-glycolide)(PLGA) …

Preparation and characterization of Tamoxifen citrate loaded nanoparticles for breast cancer therapy

R Maji, NS Dey, BS Satapathy… - International journal …, 2014 - Taylor & Francis
Background Four formulations of Tamoxifen citrate loaded polylactide-co-glycolide (PLGA)
based nanoparticles (TNPs) were developed and characterized. Their internalization by …

Development of favipiravir loaded PLGA nanoparticles entrapped in in-situ gel for treatment of Covid-19 via nasal route

V Gattani, S Dawre - Journal of drug delivery science and technology, 2023 - Elsevier
In 2019 the emergence of SARS-COV-2 caused pandemic situation worldwide and
claimed∼ 6.4 M lives (WHO 2022). Favipiravir (FAV) is recommended as a therapy for Covid …

A robust systematic design: optimization and preparation of polymeric nanoparticles of PLGA for docetaxel intravenous delivery

P Rafiei, A Haddadi - Materials Science and Engineering: C, 2019 - Elsevier
Abstract Poly (lactide-co-glycolide)(PLGA) is a biocompatible, biodegradable, and non-toxic
polymer used in a variety of biomedical and pharmaceutical applications. Polymeric …

Cardioprotective effects of curcumin-nisin based poly lactic acid nanoparticle on myocardial infarction in guinea pigs

WEE Nabofa, OO Alashe, OT Oyeyemi, AF Attah… - Scientific reports, 2018 - nature.com
Myocardial infarction (MI) is the most prevalent cause of cardiovascular death. A possible
way of preventing MI maybe by dietary supplements. The present study was thus designed …

Docetaxel-loaded human serum albumin (HSA) nanoparticles: synthesis, characterization, and evaluation

N Qu, Y Sun, Y Li, F Hao, P Qiu, L Teng, J Xie… - Biomedical engineering …, 2019 - Springer
Background Docetaxel (DTX) is an anticancer drug that is currently formulated with
polysorbate 80 and ethanol (50: 50, v/v) in clinical use. Unfortunately, this formulation …

N-trimethyl chitosan coated nano-complexes enhance the oral bioavailability and chemotherapeutic effects of gemcitabine

G Chen, D Svirskis, W Lu, M Ying, H Li, M Liu… - Carbohydrate …, 2021 - Elsevier
N-trimethyl chitosan (TMC) is a multifunctional polymer that can be used in various
nanoparticle forms in the pharmaceutical, nutraceutical and biomedical fields. In this study …