Sickle cell disease: renal manifestations and mechanisms

KA Nath, RP Hebbel - Nature Reviews Nephrology, 2015 - nature.com
Sickle cell disease (SCD) substantially alters renal structure and function, and causes
various renal syndromes and diseases. Such diverse renal outcomes reflect the uniquely …

The nephropathy of sickle cell trait and sickle cell disease

KI Ataga, SL Saraf, VK Derebail - Nature Reviews Nephrology, 2022 - nature.com
Sickle cell syndromes, including sickle cell disease (SCD) and sickle cell trait, are
associated with multiple kidney abnormalities. Young patients with SCD have elevated …

Sickle Cell Disease in Children and Adolescents: A Review of the Historical, Clinical, and Public Health Perspective of Sub‐Saharan Africa and Beyond

WI Egesa, G Nakalema, WM Waibi… - … Journal of Pediatrics, 2022 - Wiley Online Library
Sickle cell disease (SCD) is an umbrella term for a group of life‐long debilitating autosomal
recessive disorders that are caused by a single‐point mutation (Glu→ Val) that results in …

Sickle cell disease

MJ Bonner, ES Puffer, VW Willard - Textbook of pediatric …, 2010 - books.google.com
Sickle cell disease (SCD) is a group of inherited autosomal recessive disorders, including
sickle cell anemia, sickle beta-thalassemia, and other hemoglobinopathies, which are …

Sickle cell disease: clinical presentation and management of a global health challenge

ME Houwing, PJ De Pagter, EJ Van Beers, BJ Biemond… - Blood reviews, 2019 - Elsevier
Sickle cell disease is an autosomal recessive, multisystem disorder, characterised by
chronic haemolytic anaemia, painful episodes of vaso-occlusion, progressive organ failure …

The glomerulopathy of sickle cell disease

KI Ataga, VK Derebail, DR Archer - American journal of …, 2014 - Wiley Online Library
Sickle cell disease (SCD) produces many structural and functional abnormalities in the
kidney, including glomerular abnormalities. Albuminuria is the most common manifestation …

A clinically meaningful fetal hemoglobin threshold for children with sickle cell anemia during hydroxyurea therapy

JH Estepp, MP Smeltzer, G Kang, C Li… - American journal of …, 2017 - Wiley Online Library
Hydroxyurea has proven clinical benefits and is recommended to be offered to all children
with sickle cell anemia (SCA), but the optimal dosing regimen remains controversial …

Guidelines for the use of hydroxycarbamide in children and adults with sickle cell disease A British Society for Haematology Guideline.

A Qureshi, B Kaya, S Pancham… - British journal of …, 2018 - search.ebscohost.com
The article discusses findings of a study on guidelines for the use of hydroxycarbamide in
children and adults with sickle cell disease (SCD). It states that hydroxycarbamide is an …

Update on the use of hydroxyurea therapy in sickle cell disease

TE Wong, AM Brandow, W Lim… - Blood, The Journal of …, 2014 - ashpublications.org
Case 2: A 5-year-old girl with HbSS is being seen for a routine follow-up visit. She has never
had acute chest syndrome or other sickle cell–related complications. She currently has …

[HTML][HTML] Development of the InCharge health mobile app to improve adherence to hydroxyurea in patients with sickle cell disease: user-centered design approach

NM Alberts, SM Badawy, J Hodges… - JMIR mHealth and …, 2020 - mhealth.jmir.org
Background Sickle cell disease (SCD) is an inherited blood disorder causing acute
complications and chronic progressive end organ damage. SCD is associated with …