Antibodies (Abs) containing two different antigen-binding sites in one molecule are called
bispecific. Bispecific Abs (BsAbs) were first described in the 1960s, the first monoclonal …

Immunoglobulins are known to combine various effector mechanisms of the adaptive and
the innate immune system. Classical immunoglobulin functions are associated with antigen …

The specific organ placenta is much more than a filter: it is an organ that protects, feeds and
regulates the growth of the embryo. Affinity chromatography, ELISA, SDS–PAGE and matrix …

Context: As a new antibody concept, natural bispecific antibodies (nBsAbs) have been
detected in long-term passive immunization and some diseases, but their potential …

In light of the immunoprotective function of human milk and the incontestable impact of IgG
glycosylation on its immune functions, characterization of the sialylation profile of human …

In the classic paradigm, immunoglobulins are monospecific molecules that have stable
structures and two or more identical antigen-binding sites. However, we show here for the …

As shown in many studies, one of the earliest statistically significant indicators of the
development of many autoimmune diseases (ADs) is the appearance in the blood of …

In the classic paradigm, immunoglobulins represent products of clonal B cell populations,
each producing antibodies recognizing a single antigen (monospecific). There is a common …

Though hundreds of thousands of papers are currently being published on HIV/AIDS, only
tens of hundreds of them are devoted to the antibodies generated during the disease. Most …

The polyreactivity of binding (formation of antibody (AB) complexes not only with specific but
also with foreign antigens) is a widespread phenomenon that in some cases can be caused …