Interferences in immunoassays: review and practical algorithm

L Wauthier, M Plebani, J Favresse - Clinical Chemistry and …, 2022 - degruyter.com
Immunoassays are currently the methods of choice for the measurement of a large panel of
complex and heterogenous molecules owing to full automation, short turnaround time, high …

Cytokines as biomarkers in rheumatoid arthritis

A Burska, M Boissinot, F Ponchel - Mediators of inflammation, 2014 - Wiley Online Library
RA is a complex disease that develops as a series of events often referred to as disease
continuum. RA would benefit from novel biomarker development for diagnosis where new …

Heterophilic antibody interference in immunometric assays

N Bolstad, DJ Warren, K Nustad - Best practice & research Clinical …, 2013 - Elsevier
Immunometric assays are inherently vulnerable to interference from heterophilic antibodies,
endogenous antibodies that bind assay antibodies. The consequences of such interference …

Quantitative detection of α-Synuclein and Tau oligomers and other aggregates by digital single particle counting

L Blömeke, M Pils, V Kraemer-Schulien… - npj Parkinson's …, 2022 - nature.com
The pathological hallmark of neurodegenerative diseases is the formation of toxic oligomers
by proteins such as alpha-synuclein (aSyn) or microtubule-associated protein tau (Tau) …

Other markers of medullary thyroid cancer, not only calcitonin

S Censi, J Manso, C Mian - European Journal of Endocrinology, 2023 - academic.oup.com
Background Medullary thyroid cancer (MTC) is a rare neuroendocrine tumor originating from
parafollicular C-cells. It represents 2% of all thyroid malignancies and 0.4-1.4% of all thyroid …

Interference from heterophilic antibodies in troponin testing. Case report and systematic review of the literature

G Lippi, R Aloe, T Meschi, L Borghi, G Cervellin - Clinica Chimica Acta, 2013 - Elsevier
Heterophilic antibodies, comprising both “true” heterophilic antibodies and human anti-
mouse antibodies (HAMA), represent an important source of interference in laboratory …

Improving the measurement of serum thyroglobulin with mass spectrometry

AN Hoofnagle, MY Roth - The Journal of Clinical Endocrinology …, 2013 - academic.oup.com
Context: Serum thyroglobulin (Tg) measurements are central to the management of patients
treated for differentiated thyroid carcinoma. For decades, Tg measurements have relied on …

High-sensitivity methods for cardiac troponins: The mission is not over yet

A Clerico, M Zaninotto, C Passino, A Padoan… - Advances in Clinical …, 2021 - Elsevier
The measurement of cardiac troponin (cTn) is recommended by all guidelines as the gold
standard for the differential diagnosis of Acute Coronary Syndromes. The aim of this review …

Potential false‐positive reasons for SARS‐CoV‐2 antibody testing and its solution

Q Ye, T Zhang, D Lu - Journal of Medical Virology, 2021 - Wiley Online Library
Abstract Coronavirus disease 2019 (COVID‐19) has brought a huge impact on global health
and the economy. Early diagnosis of severe acute respiratory syndrome coronavirus 2 …

Interference of medical contrast media on laboratory testing

G Lippi, MD Daves, CM Mattiuzzi - Biochemia Medica, 2014 - hrcak.srce.hr
Sažetak The use of contrast media such as organic iodine molecules and gadolinium
contrast agents is commonplace in diagnostic imaging. Although there is widespread …