Neutralisation of systemic anticoagulation with heparin in cardiac surgery with
cardiopulmonary bypass requires protamine administration. If adequately dosed, protamine …

Introduction Pulmonary vascular dysfunction, pulmonary hypertension (PH), and resulting
right ventricular (RV) failure occur in many critical illnesses and may be associated with a …

The importance of right ventricular (RV) function in cardiovascular disease and cardiac
surgery has been recognized for several years. RV dysfunction has been shown to be a …

Despite more than a half century of “safe” cardiopulmonary bypass (CPB), the evidence
base surrounding the conduct of anticoagulation therapy for CPB has not been organized …

The importance of right ventricular (RV) function in cardiovascular disease and cardiac
surgery has been recognized for several years. RV dysfunction has been shown to be a …

Introduction: Unfractionated heparin is a strongly anionic anticoagulant used extensively in
medicine to prevent blood clotting. In the case of an emergency bleeding in response to …

Despite more than a half century of “safe” cardiopulmonary bypass (CPB), the evidence
base surrounding the conduct of anticoagulation for CPB has not been organized into a …

Background Children with primary pulmonary hypertension (PHT) are a high‐risk group who
require assessment by cardiac catheterization under anaesthesia. Complications, including …

Pulmonary hypertension is an important prognostic factor in cardiac surgery associated with
increased morbidity and mortality. With the aging population and the associated increase …

Despite significant advances in surgical technique and strategies for tissue/organ protection,
cardiac surgery involving cardiopulmonary bypass is a profound stressor on the human …