Direct and indirect evidence suggests that Na+/K+-ATPase activity is reduced or insufficient
to maintain ionic balances during and immediately after episodes of ischemia …

3.5. 1. Release of amino acids from glial cells 3.6. Release via the high affinity uptake
systems 3.6. 1. General properties of the carrier proteins 3.6. 2. Homoexchange and …

Revision accepted: October 6, 1993 y-Aminobutyric acid (GABA) is generally considered the
major inhibitory neurotransmitter within the mammalian CNS, playing a crucial role in the …

Background and Purpose It is known that the extracellular accumulation of glutamate during
anoxia/ischemia is responsible for initiating neuronal injury. However, little information is …

In this study, we investigated the in vitro effect of exogenously administered insulin on the
susceptibility to oxidative stress and on the accumulation of the amino acid …

Evidence suggests that oxidative stress is involved in the pathophysiology of diabetic
complications and that insulin has a neuroprotective role in oxidative stress conditions. In …

In recent years, enough evidence has accumulated to assert that cardiotonic steroids, Na+,
K+-ATPase ligands, play an integral role in the physiological and pathophysiological …

The γ-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in vertebrate CNS.
At GABAergic synapses, a high-affinity transporter exists, which is responsible for GABA …

In this work, we evaluated the effects of streptozotocin (STZ)‐induced hyperglycemia and an
acute episode of insulin‐induced hypoglycemia in plasma amino acids and cortical …

The lifespan of the predominant inhibitory neurotransmitter in the central nervous system, γ-
aminobutyric acid (GABA), is determined by its uptake into neurons and glia, through high …