Shigella comprises four species of human-restricted pathogens causing bacillary dysentery.
While Shigella possesses multiple genetic loci contributing to virulence, a type III secretion …

The type III secretion system (T3SS) is a virulence apparatus used by many Gram-negative
pathogenic bacteria to cause infections. Pathogens utilizing a T3SS are responsible for …

Shigella spp. are one of the leading causes of infectious diarrheal diseases. They are
Escherichia coli pathovars that are characterized by the harboring of a large plasmid that …

Various Gram-negative bacteria possess a specialized membrane-bound protein secretion
system known as the Type III secretion system (T3SS), which transports the bacterial effector …

The type III secretion system (T3SS) is a large, transmembrane protein machinery used by
various pathogenic gram‐negative bacteria to transport virulence factors into the host cell …

Shigella spp. cause hundreds of millions of intestinal infections each year. They target the
mucosa of the human colon and are an important model of intracellular bacterial …

Virulence-associated bacterial type III secretion systems are multiprotein molecular
machines that promote the pathogenicity of bacteria towards eukaryotic host cells. These …

Bacteria use type III secretion injectisomes to inject effector proteins into eukaryotic target
cells. Recruitment of effectors to the machinery and the resulting export hierarchy involve the …

The type III secretion system is the common core of two bacterial molecular machines: the
flagellum and the injectisome. The flagellum is the most widely distributed prokaryotic …

Many bacterial pathogens use a type III secretion system (T3SS) to manipulate host cells.
Protein secretion by the T3SS injectisome is activated upon contact to any host cell, and it …