Anti-tumor necrosis factor (TNF) biological therapy has generally been accepted as a
standard therapeutic option in inflammatory bowel disease (IBD) patient who are refractory …

Precision medicine is part of 5 focus areas of the Challenges in IBD Research 2024
research document, which also includes preclinical human IBD mechanisms, environmental …

Introduction: Crohn's disease (CD) is a disease that manifests mainly as chronic
inflammation of the gastrointestinal tract, which is still not well understood in terms of its …

Background: A number of patients with Crohn's disease (CD) suffer from loss of response to
infliximab (IFX) therapy. Splenic volume is reported to be enlarged in patients with CD …

Purpose Accurately predicting the treatment response in patients with Crohn's disease (CD)
receiving infliximab therapy is crucial for clinical decision-making. We aimed to construct a …

Inflammatory bowel disease (IBD) is a collective term for two diseases: ulcerative colitis (UC)
and Crohn's disease (CD). There are many factors, eg, genetic, environmental and …

Objective To investigate the predictive value of the prognostic nutritional index (PNI) for the
effectiveness of infliximab (IFX) in patients with Crohn's disease (CD). Methods All data were …

Background Accurate prediction of treatment response in Crohn's disease (CD) patients
undergoing infliximab (IFX) therapy is essential for clinical decision-making. Our goal was to …

Crohn's disease and ulcerative colitis, the two most common inflammatory bowel diseases
(IBD), are characterized by chronic relapsing inflammation. Although recent progress …

Background: Stricture in patients with Crohn's disease (CD) carries a high risk of CD-related
surgery in the course of the disease. The aim of this study was to assess the rate of …