SARS-CoV-2 evolution in the Omicron era

C Roemer, DJ Sheward, R Hisner, F Gueli… - Nature …, 2023 - nature.com
Abstract Since SARS-CoV-2 BA. 5 (Omicron) emerged and spread in 2022, Omicron
lineages have markedly diversified. Here we review the evolutionary trajectories and …

[HTML][HTML] Comparing COVID-19 vaccines for their characteristics, efficacy and effectiveness against SARS-CoV-2 and variants of concern: a narrative review

T Fiolet, Y Kherabi, CJ MacDonald, J Ghosn… - Clinical Microbiology …, 2022 - Elsevier
Background Vaccines are critical cost-effective tools to control the coronavirus disease 2019
(COVID-19) pandemic. However, the emergence of variants of the severe acute respiratory …

[HTML][HTML] Global impact of the first year of COVID-19 vaccination: a mathematical modelling study

OJ Watson, G Barnsley, J Toor, AB Hogan… - The Lancet infectious …, 2022 - thelancet.com
Background The first COVID-19 vaccine outside a clinical trial setting was administered on
Dec 8, 2020. To ensure global vaccine equity, vaccine targets were set by the COVID-19 …

[HTML][HTML] Neurological and psychiatric risk trajectories after SARS-CoV-2 infection: an analysis of 2-year retrospective cohort studies including 1 284 437 patients

M Taquet, R Sillett, L Zhu, J Mendel… - The Lancet …, 2022 - thelancet.com
Background COVID-19 is associated with increased risks of neurological and psychiatric
sequelae in the weeks and months thereafter. How long these risks remain, whether they …

Clinical severity of, and effectiveness of mRNA vaccines against, covid-19 from omicron, delta, and alpha SARS-CoV-2 variants in the United States: prospective …

AS Lauring, MW Tenforde, JD Chappell, M Gaglani… - bmj, 2022 - bmj.com
Objectives To characterize the clinical severity of covid-19 associated with the alpha, delta,
and omicron SARS-CoV-2 variants among adults admitted to hospital and to compare the …

[HTML][HTML] Comparative analysis of the risks of hospitalisation and death associated with SARS-CoV-2 omicron (B. 1.1. 529) and delta (B. 1.617. 2) variants in England: a …

T Nyberg, NM Ferguson, SG Nash, HH Webster… - The lancet, 2022 - thelancet.com
Background The omicron variant (B. 1.1. 529) of SARS-CoV-2 has demonstrated partial
vaccine escape and high transmissibility, with early studies indicating lower severity of …

[HTML][HTML] SARS-CoV-2 Omicron variant replication in human bronchus and lung ex vivo

KPY Hui, JCW Ho, M Cheung, K Ng, RHH Ching, K Lai… - Nature, 2022 - nature.com
The emergence of SARS-CoV-2 variants of concern with progressively increased
transmissibility between humans is a threat to global public health. The Omicron variant of …

Virological characteristics of the SARS-CoV-2 Omicron BA. 2 subvariants, including BA. 4 and BA. 5

I Kimura, D Yamasoba, T Tamura, N Nao, T Suzuki… - Cell, 2022 - cell.com
After the global spread of the SARS-CoV-2 Omicron BA. 2, some BA. 2 subvariants,
including BA. 2.9. 1, BA. 2.11, BA. 2.12. 1, BA. 4, and BA. 5, emerged in multiple countries …

[HTML][HTML] Attenuated fusogenicity and pathogenicity of SARS-CoV-2 Omicron variant

R Suzuki, D Yamasoba, I Kimura, L Wang, M Kishimoto… - Nature, 2022 - nature.com
The emergence of the Omicron variant of SARS-CoV-2 is an urgent global health concern. In
this study, our statistical modelling suggests that Omicron has spread more rapidly than the …

[HTML][HTML] Enhanced fusogenicity and pathogenicity of SARS-CoV-2 Delta P681R mutation

A Saito, T Irie, R Suzuki, T Maemura, H Nasser, K Uriu… - Nature, 2022 - nature.com
During the current coronavirus disease 2019 (COVID-19) pandemic, a variety of mutations
have accumulated in the viral genome of severe acute respiratory syndrome coronavirus 2 …